tert-butyl (3-benzyloxy)-4-formyl-5-(trifluoromethylsulfonyloxy)benzoate

Base Information

• Chemical Name: tert-butyl (3-benzyloxy)-4-formyl-5-(trifluoromethylsulfonyloxy)benzoate
• CAS No.: 1246012-82-7
• Molecular Formula: C₂₀H₁₉F₃O₇S
• Molecular Weight: 460.428
• Mol file: 1246012-82-7.mol

Synonyms:tert-butyl (3-benzyloxy)-4-formyl-5-(trifluoromethylsulfonyloxy)benzoate

Chemical Property of tert-butyl (3-benzyloxy)-4-formyl-5-(trifluoromethylsulfonyloxy)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl (3-benzyloxy)-4-formyl-5-(trifluoromethylsulfonyloxy)benzoate

There total 1 articles about tert-butyl (3-benzyloxy)-4-formyl-5-(trifluoromethylsulfonyloxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

trifluoromethylsulfonic anhydride (358-23-6) + tert-butyl (3-benzyloxy)-4-formyl-5-hydroxybenzoate (1246012-81-6) → tert-butyl (3-benzyloxy)-4-formyl-5-(trifluoromethylsulfonyloxy)benzoate (1246012-82-7)

Guidance literature:

With potassium phosphate; In water; toluene; at 0 - 20 ℃;

DOI:10.1021/ol101595u

Reference yield: 64.0%

(1S,5S)-6-trityl-3,6-diazabicyclo[3.1.0]hexan-2-one (1246012-66-7) + tert-butyl (3-benzyloxy)-4-formyl-5-(trifluoromethylsulfonyloxy)benzoate (1246012-82-7) → tert-butyl (3-benzyloxy)-4-formyl-5-hydroxybenzoate (1246012-81-6) + C42H38N2O5 (1246012-83-8)

Guidance literature:

With potassium phosphate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; In 1,4-dioxane; at 80 ℃; for 18h; Inert atmosphere;

DOI:10.1021/ol101595u

upstream raw materials:

trifluoromethylsulfonic anhydride

tert-butyl (3-benzyloxy)-4-formyl-5-hydroxybenzoate

Downstream raw materials:

tert-butyl (3-benzyloxy)-4-formyl-5-hydroxybenzoate

C₄₂H₃₈N₂O₅