3-butyl-4-<<2'-(N-triphenylmethyl)tetrazol-5-yl>biphenyl-4-yl>methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

Base Information

• Chemical Name: 3-butyl-4-<<2'-(N-triphenylmethyl)tetrazol-5-yl>biphenyl-4-yl>methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
• CAS No.: 220371-15-3
• Molecular Formula: C₄₄H₃₈N₆O₂S
• Molecular Weight: 714.891
• Mol file: 220371-15-3.mol

Synonyms:3-butyl-4-<<2'-(N-triphenylmethyl)tetrazol-5-yl>biphenyl-4-yl>methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

Chemical Property of 3-butyl-4-<<2'-(N-triphenylmethyl)tetrazol-5-yl>biphenyl-4-yl>methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-butyl-4-<<2'-(N-triphenylmethyl)tetrazol-5-yl>biphenyl-4-yl>methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

There total 3 articles about 3-butyl-4-<<2'-(N-triphenylmethyl)tetrazol-5-yl>biphenyl-4-yl>methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

N-(triphenylmethyl)-5-<4'-(bromomethyl)biphenyl-2-yl>tetrazole (133051-88-4) + 3-butyl-2H-1,2,4-benzothiadiazine 1,1-dioxide (6518-87-2) → 3-butyl-4-<<2'-(N-triphenylmethyl)tetrazol-5-yl>biphenyl-4-yl>methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide (220371-15-3) + 3-butyl-2-<<2'-(N-triphenylmethyl)tetrazol-5-yl>biphenyl-4-yl>methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide (220371-14-2)

Guidance literature:

With potassium carbonate; potassium iodide; In acetonitrile; for 72h; Heating;

DOI:10.1002/jccs.199800121

Reference yield:

2-AMINOBENZENESULFONAMIDE (3306-62-5) → 3-butyl-4-<<2'-(N-triphenylmethyl)tetrazol-5-yl>biphenyl-4-yl>methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide (220371-15-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / toluene-4-sulfonic acid / toluene / 96 h / Heating

2: 28 percent / K₂CO₃, KI / acetonitrile / 72 h / Heating

With potassium carbonate; toluene-4-sulfonic acid; potassium iodide; In toluene; acetonitrile;

DOI:10.1002/jccs.199800121

Reference yield:

valeric acid (109-52-4) → 3-butyl-4-<<2'-(N-triphenylmethyl)tetrazol-5-yl>biphenyl-4-yl>methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide (220371-15-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 68 percent / toluene-4-sulfonic acid / toluene / 96 h / Heating

2: 28 percent / K₂CO₃, KI / acetonitrile / 72 h / Heating

With potassium carbonate; toluene-4-sulfonic acid; potassium iodide; In toluene; acetonitrile;

DOI:10.1002/jccs.199800121

upstream raw materials:

N-(triphenylmethyl)-5-<4'-(bromomethyl)biphenyl-2-yl>tetrazole

3-butyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

2-AMINOBENZENESULFONAMIDE

valeric acid