2-(Allylthio)pyrazine

Base Information

• Chemical Name: 2-(Allylthio)pyrazine
• CAS No.: 164352-89-0
• Molecular Formula: C₇H₈N₂S
• Molecular Weight: 152.22
• DSSTox Substance ID: DTXSID00167748
• Nikkaji Number: J818.125J
• Wikidata: Q83037190
• Mol file: 164352-89-0.mol

Synonyms:2-(allylthio)pyrazine

Chemical Property of 2-(Allylthio)pyrazine

Chemical Property:

• Vapor Pressure: 0.0664mmHg at 25°C
• Boiling Point: 238.2°Cat760mmHg
• Flash Point: 97.8°C
• Density: 1.13g/cm³
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 152.04081944
• Heavy Atom Count: 10
• Complexity: 106

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CCSC1=NC=CN=C1

Technology Process of 2-(Allylthio)pyrazine

There total 3 articles about 2-(Allylthio)pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

allyl bromide (106-95-6) + 2-mercaptopyrazine (38521-06-1) → IR(Paraffin oil) + 2-(allylthio)pyrazine (164352-89-0)

Guidance literature:

In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; triethylamine;

Reference yield:

2-chloropyrazin (14508-49-7) + prop-2-ene-1-thiol (870-23-5) → 2-(allylthio)pyrazine (164352-89-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

DOI:10.1021/jacs.8b09595

Reference yield:

→ IR(Paraffin oil) + 2-(allylthio)pyrazine (164352-89-0)

Guidance literature:

upstream raw materials:

allyl bromide

2-mercaptopyrazine

2-chloropyrazin

prop-2-ene-1-thiol