(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride

Base Information

Chemical Name:(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride
CAS No.:1428847-19-1
Molecular Formula:C₂₉H₃₁Cl₂F₂N₃O₇S*ClH
Molecular Weight:711.011
Hs Code.:

(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride

Synonyms:(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride

Suppliers and Price of (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride

There total 7 articles about (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.5%

: 1428847-26-0
(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide

: 1428847-19-1
(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride

Guidance literature:: With hydrogen; In 1,4-dioxane; dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 1428847-25-9
(S)-4-(2-(2-((4-(N-(tert-butoxycarbonyl)methylsulfonamido)-benzyl)(methyl)amino)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)-phenyl)ethyl)-3,5-dichloropyridine 1-oxide

: 1428847-19-1
(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride

Guidance literature:: With hydrogenchloride; In dichloromethane; at 20 ℃;

Reference yield:

: 1428847-22-6
allyl 2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetate

: 1428847-19-1
(S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(methyl(4-(methylsulfonamido)benzyl)-amino)acetoxy)ethyl)pyridine 1-oxide hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: dmap / dichloromethane / 1 h / 20 °C

2: water; lithium hydroxide / tetrahydrofuran / 72 h / 20 °C

3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane; acetonitrile / 48 h / 20 °C

4: hydrogenchloride / dichloromethane / 20 °C

With hydrogenchloride; dmap; water; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium hydroxide; In tetrahydrofuran; dichloromethane; acetonitrile;