3-(4-chloro-phenyl)-5-phenyl-isothiazole-4-carboxylic acid tert-butylester

Base Information

Chemical Name:3-(4-chloro-phenyl)-5-phenyl-isothiazole-4-carboxylic acid tert-butylester
CAS No.:1101130-07-7
Molecular Formula:C₂₀H₁₈ClNO₂S
Molecular Weight:371.887
Hs Code.:

Synonyms:3-(4-chloro-phenyl)-5-phenyl-isothiazole-4-carboxylic acid tert-butylester

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Chemical Property of 3-(4-chloro-phenyl)-5-phenyl-isothiazole-4-carboxylic acid tert-butylester

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Technology Process of 3-(4-chloro-phenyl)-5-phenyl-isothiazole-4-carboxylic acid tert-butylester

There total 1 articles about 3-(4-chloro-phenyl)-5-phenyl-isothiazole-4-carboxylic acid tert-butylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1101130-06-6
5-bromo-3-(4-chloro-phenyl)-isothiazole-4-carboxylic acid tert-butyl ester

: 98-80-6
phenylboronic acid

: 1101130-07-7
3-(4-chloro-phenyl)-5-phenyl-isothiazole-4-carboxylic acid tert-butylester

Guidance literature:: With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,2-dimethoxyethane; water; at 100 ℃; for 0.25h;

Reference yield:

: 1101130-07-7
3-(4-chloro-phenyl)-5-phenyl-isothiazole-4-carboxylic acid tert-butylester

: 1101130-08-8
3-(4-chloro-phenyl)-5-phenyl-isothiazole-4-carboxylic acid

Guidance literature:: 3-(4-chloro-phenyl)-5-phenyl-isothiazole-4-carboxylic acid tert-butylester; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 24h;

With sodium hydroxide; In diethyl ether; water;

With hydrogenchloride; In water;