(R)-2-(4-isobutylphenyl)-N-[2-(N-morpholinyl)ethyl]propionamide hydrochloride

Base Information

Chemical Name:(R)-2-(4-isobutylphenyl)-N-[2-(N-morpholinyl)ethyl]propionamide hydrochloride
CAS No.:454701-20-3
Molecular Formula:C₁₉H₃₀N₂O₂*ClH
Molecular Weight:354.92
Hs Code.:

Synonyms:(R)-2-(4-isobutylphenyl)-N-[2-(N-morpholinyl)ethyl]propionamide hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-(4-isobutylphenyl)-N-[2-(N-morpholinyl)ethyl]propionamide hydrochloride

Chemical Property:

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Technology Process of (R)-2-(4-isobutylphenyl)-N-[2-(N-morpholinyl)ethyl]propionamide hydrochloride

There total 2 articles about (R)-2-(4-isobutylphenyl)-N-[2-(N-morpholinyl)ethyl]propionamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 114978-05-1
(R)-2-(4-isobutylphenyl)propionyl chloride

: 2038-03-1
4-(2-AMINOETHYL)MORPHOLINE

: 454701-20-3
(R)-2-(4-isobutylphenyl)-N-[2-(N-morpholinyl)ethyl]propionamide hydrochloride

Guidance literature:: (R)-2-(4-isobutylphenyl)propionyl chloride; 4-(2-AMINOETHYL)MORPHOLINE; In dichloromethane; at 20 - 40 ℃;

With ethanol; acetyl chloride; at 20 ℃; for 2h;

Reference yield:

: 51146-57-7,58560-75-1
(R)-ibuprofene

: 454701-20-3
(R)-2-(4-isobutylphenyl)-N-[2-(N-morpholinyl)ethyl]propionamide hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: thionyl chloride / 3 h / Reflux

2.1: dichloromethane / 20 - 40 °C

2.2: 2 h / 20 °C

With thionyl chloride; In dichloromethane;