5-deoxy-5-azido-2,3-di-O-benzoyl-1-O-trichloroacetimido-D-ribofuranose

Base Information

• Chemical Name: 5-deoxy-5-azido-2,3-di-O-benzoyl-1-O-trichloroacetimido-D-ribofuranose
• CAS No.: 918800-28-9
• Molecular Formula: C₂₁H₁₇Cl₃N₄O₆
• Molecular Weight: 527.748
• Mol file: 918800-28-9.mol

Synonyms:5-deoxy-5-azido-2,3-di-O-benzoyl-1-O-trichloroacetimido-D-ribofuranose

Chemical Property of 5-deoxy-5-azido-2,3-di-O-benzoyl-1-O-trichloroacetimido-D-ribofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-deoxy-5-azido-2,3-di-O-benzoyl-1-O-trichloroacetimido-D-ribofuranose

There total 3 articles about 5-deoxy-5-azido-2,3-di-O-benzoyl-1-O-trichloroacetimido-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H17N3O6 + trichloroacetonitrile (545-06-2) → 5-deoxy-5-azido-2,3-di-O-benzoyl-1-O-trichloroacetimido-D-ribofuranose (918800-28-9)

Guidance literature:

With potassium carbonate; In dichloromethane; at 20 ℃; for 8h;

Reference yield:

C19H17N3O6 + trichloroacetonitrile (545-06-2) → 5-deoxy-5-azido-2,3-di-O-benzoyl-1-O-trichloroacetimido-D-ribofuranose (918800-28-9) + 5-deoxy-5-azido-2,3-di-O-benzoyl-1-O-tricloroacetimido-α-D-ribofuranose

Guidance literature:

With potassium carbonate; In dichloromethane; at 20 ℃; for 8h;

Reference yield:

p-methylphenyl 5-deoxy-5-azido-2,3-di-O-benzoyl-1-thio-β-D-ribofuranose (817195-49-6) → 5-deoxy-5-azido-2,3-di-O-benzoyl-1-O-trichloroacetimido-D-ribofuranose (918800-28-9)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide / acetone / 2 h / -10 °C

2: potassium carbonate / dichloromethane / 8 h / 20 °C

With N-Bromosuccinimide; potassium carbonate; In dichloromethane; acetone;

upstream raw materials:

trichloroacetonitrile

p-methylphenyl 5-deoxy-5-azido-2,3-di-O-benzoyl-1-thio-β-D-ribofuranose

Downstream raw materials:

C₄₄H₅₂N₁₀O₁₈

C₄₀H₄₄N₁₂O₁₆

(2S,3R,4S,5R)-2-[(2S,3R,4R,5S,6R)-3-Amino-2-((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxy-cyclohexyloxy)-5-hydroxy-6-hydroxymethyl-tetrahydro-pyran-4-yloxy]-5-aminomethyl-tetrahydro-furan-3,4-diol

C₃₁H₃₄N₁₂O₁₂