[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1-cyclopentyl-1H-indol-5-yl]-carbamic acid cyclopentyl ester

Base Information

Chemical Name:[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1-cyclopentyl-1H-indol-5-yl]-carbamic acid cyclopentyl ester
CAS No.:107786-67-4
Molecular Formula:C₃₄H₃₇N₃O₆S
Molecular Weight:615.75
Hs Code.:

Synonyms:[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1-cyclopentyl-1H-indol-5-yl]-carbamic acid cyclopentyl ester

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Chemical Property of [3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1-cyclopentyl-1H-indol-5-yl]-carbamic acid cyclopentyl ester

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Technology Process of [3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1-cyclopentyl-1H-indol-5-yl]-carbamic acid cyclopentyl ester

There total 3 articles about [3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1-cyclopentyl-1H-indol-5-yl]-carbamic acid cyclopentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 98-10-2
benzenesulfonamide

: 107786-56-1
4-[(1-cyclopentyl-5-{[(cyclopentyloxy)carbonyl]amino}-1H-indol-3-yl)methyl]-3-methoxybenzoicacid

: 107786-67-4
[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1-cyclopentyl-1H-indol-5-yl]-carbamic acid cyclopentyl ester

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 18h;
DOI:10.1021/jm00168a037

Reference yield:

: 137-43-9
Cyclopentyl bromide

: 107786-67-4
[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1-cyclopentyl-1H-indol-5-yl]-carbamic acid cyclopentyl ester

Guidance literature:: Multi-step reaction with 2 steps

2: 89 percent / 4-(dimethylamino)pyridine, 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride / CH₂Cl₂ / 18 h

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;
DOI:10.1021/jm00168a037

Reference yield:

: 107754-12-1
4-[5-(cyclopentyloxycarbonyl)amino-1H-indol-3-ylmethyl]-3-methoxy-benzoic acid methylester

: 107786-67-4
[3-(4-Benzenesulfonylaminocarbonyl-2-methoxy-benzyl)-1-cyclopentyl-1H-indol-5-yl]-carbamic acid cyclopentyl ester

Guidance literature:: Multi-step reaction with 2 steps

2: 89 percent / 4-(dimethylamino)pyridine, 1-<3-(dimethylamino)propyl>-3-ethylcarbodiimide hydrochloride / CH₂Cl₂ / 18 h

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;
DOI:10.1021/jm00168a037