carbonic acid 1-cyano-4-[2-(3-methoxy-prop-1-ynyl)-phenyl]-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester

Base Information

• Chemical Name: carbonic acid 1-cyano-4-[2-(3-methoxy-prop-1-ynyl)-phenyl]-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester
• CAS No.: 713496-88-9
• Molecular Formula: C₂₅H₂₂N₂O₆
• Molecular Weight: 446.459

Synonyms:carbonic acid 1-cyano-4-[2-(3-methoxy-prop-1-ynyl)-phenyl]-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester

Chemical Property of carbonic acid 1-cyano-4-[2-(3-methoxy-prop-1-ynyl)-phenyl]-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of carbonic acid 1-cyano-4-[2-(3-methoxy-prop-1-ynyl)-phenyl]-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester

There total 3 articles about carbonic acid 1-cyano-4-[2-(3-methoxy-prop-1-ynyl)-phenyl]-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

1-iodo-2-(3-methoxy-prop-1-ynyl)-benzene (713496-95-8) + carbonic acid 1-cyano-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester (713497-02-0) → carbonic acid 1-cyano-4-[2-(3-methoxy-prop-1-ynyl)-phenyl]-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester (713496-88-9)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In toluene; at 20 ℃;

DOI:10.1016/j.bmcl.2004.02.096

Reference yield:

1,2-Diiodobenzene (615-42-9) → carbonic acid 1-cyano-4-[2-(3-methoxy-prop-1-ynyl)-phenyl]-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester (713496-88-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 43 percent / Pd(PPh₃)4; CuI; Et₃N / toluene / 20 °C

2: 61 percent / Pd(PPh₃)4; CuI; Et₃N / toluene / 20 °C

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In toluene; 1: Sonogashira coupling / 2: Sonogashira coupling;

DOI:10.1016/j.bmcl.2004.02.096

Reference yield:

2-(o-nitrophenyl)prop-1-yl p-nitrophenyl carbonate → carbonic acid 1-cyano-4-[2-(3-methoxy-prop-1-ynyl)-phenyl]-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester (713496-88-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / CH₂Cl₂ / 20 °C

2: 61 percent / Pd(PPh₃)4; CuI; Et₃N / toluene / 20 °C

With pyridine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In dichloromethane; toluene; 2: Sonogashira coupling;

DOI:10.1016/j.bmcl.2004.02.096

upstream raw materials:

1-iodo-2-(3-methoxy-prop-1-ynyl)-benzene

carbonic acid 1-cyano-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester

1,2-Diiodobenzene

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 713496-88-9 carbonic acid 1-cyano-4-[2-(3-methoxy-prop-1-ynyl)-phenyl]-but-3-ynyl ester 2-(2-nitro-phenyl)-propyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send