Technology Process of tert-butyl 2-[4-(triisopropylsilyloxy)phenyl]-[1,1,2,2,-2H4]ethylcarbamate
There total 4 articles about tert-butyl 2-[4-(triisopropylsilyloxy)phenyl]-[1,1,2,2,-2H4]ethylcarbamate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C17H25(2)H2NOSi;
With
aluminium trichloride; lithium aluminium deuteride;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
With
potassium carbonate;
In
tetrahydrofuran; water;
at 20 ℃;
for 3h;
di-tert-butyl dicarbonate;
With
potassium carbonate;
In
tetrahydrofuran; water;
at 20 ℃;
for 3h;
DOI:10.1080/00397910500466074
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium methoxide; methanol-d4 / 2 h / 20 °C
2.1: lithium aluminum deuteride; aluminum chloride / tetrahydrofuran / 1 h / 20 °C
2.2: potassium carbonate / tetrahydrofuran; H2O / 3 h / 20 °C
2.3: 320 mg / potassium carbonate / tetrahydrofuran; H2O / 3 h / 20 °C
With
aluminium trichloride; lithium aluminium deuteride; d(4)-methanol; sodium methylate;
In
tetrahydrofuran;
DOI:10.1080/00397910500466074
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 84 percent / imidazole / dimethylformamide / 24.5 h / 0 - 20 °C
2.1: sodium methoxide; methanol-d4 / 2 h / 20 °C
3.1: lithium aluminum deuteride; aluminum chloride / tetrahydrofuran / 1 h / 20 °C
3.2: potassium carbonate / tetrahydrofuran; H2O / 3 h / 20 °C
3.3: 320 mg / potassium carbonate / tetrahydrofuran; H2O / 3 h / 20 °C
With
1H-imidazole; aluminium trichloride; lithium aluminium deuteride; d(4)-methanol; sodium methylate;
In
tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1080/00397910500466074
