(2R,4S)-5-biphenyl-4-yl-2-methyl-4-[(pyridazine-4-carbonyl)-amino]-pentanoic acid

Base Information

Chemical Name:(2R,4S)-5-biphenyl-4-yl-2-methyl-4-[(pyridazine-4-carbonyl)-amino]-pentanoic acid
CAS No.:1257266-04-8
Molecular Formula:C₂₃H₂₃N₃O₃
Molecular Weight:389.454
Hs Code.:

Synonyms:(2R,4S)-5-biphenyl-4-yl-2-methyl-4-[(pyridazine-4-carbonyl)-amino]-pentanoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,4S)-5-biphenyl-4-yl-2-methyl-4-[(pyridazine-4-carbonyl)-amino]-pentanoic acid

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Technology Process of (2R,4S)-5-biphenyl-4-yl-2-methyl-4-[(pyridazine-4-carbonyl)-amino]-pentanoic acid

There total 1 articles about (2R,4S)-5-biphenyl-4-yl-2-methyl-4-[(pyridazine-4-carbonyl)-amino]-pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50681-25-9
pyridazine-4-carboxylic acid

: 149690-12-0
(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoic acid ethyl ester hydrochloride

: 1257266-04-8
(2R,4S)-5-biphenyl-4-yl-2-methyl-4-[(pyridazine-4-carbonyl)-amino]-pentanoic acid

Guidance literature:: pyridazine-4-carboxylic acid; With benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoic acid ethyl ester hydrochloride; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 18h;