2,4-Dithiouridine

Base Information

• Chemical Name: 2,4-Dithiouridine
• CAS No.: 13239-96-8
• Molecular Formula: C₉H₁₂N₂O₄S₂
• Molecular Weight: 276.337
• Mol file: 13239-96-8.mol

Synonyms:2,4-Dithiouridine

Chemical Property of 2,4-Dithiouridine

Chemical Property:

• Refractive Index: 1.79
• PSA: 154.82000
• LogP: -0.11330
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly, Sonicated)

Purity/Quality:

98%Min ^*data from raw suppliers

2,4-Dithiouridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,4-Dithiouridine (cas# 13239-96-8) is a compound useful in organic synthesis.

Technology Process of 2,4-Dithiouridine

There total 2 articles about 2,4-Dithiouridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2',3',5'-tri-O-acetyl-2,4-dithiouridine (28542-32-7) → 2,4-Dithiouridin (13239-96-8)

Guidance literature:

With sodium methylate; In methanol; for 4h; Heating;

DOI:10.1016/j.bmc.2008.05.013

Reference yield:

→ 2,4-Dithiouridin (13239-96-8)

Guidance literature:

2',3',5'-Tri-O-benzoyl-4-thio-uridin, 1) P2S5/K2S/Tetralin, Δ(175-180grad), 2) Me-OH/MeONa;

upstream raw materials:

2',3',5'-tri-O-acetyl-2,4-dithiouridine

Refernces

• 1、 Ueda,Nishino. "Optical properties of thiopyrimidine nucleosides.". . p. 920 - 926. Retrieved 2007/10/07.