C₄₀H₄₈N₆O₉

Base Information

Chemical Name:C₄₀H₄₈N₆O₉
CAS No.:1379654-44-0
Molecular Formula:C₄₀H₄₈N₆O₉
Molecular Weight:756.856
Hs Code.:

C<sub>40</sub>H<sub>48</sub>N<sub>6</sub>O<sub>9</sub>

Synonyms:C₄₀H₄₈N₆O₉

Suppliers and Price of C₄₀H₄₈N₆O₉

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₄₀H₄₈N₆O₉

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₄₀H₄₈N₆O₉

There total 15 articles about C₄₀H₄₈N₆O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1379654-60-0
C₅₄H₆₀N₆O₉

: 1379654-44-0
C₄₀H₄₈N₆O₉

Guidance literature:: With palladium 10% on activated carbon; In ethanol; cyclohexa-1,4-diene; at 20 ℃; for 168h;
DOI:10.1002/chem.201103185

Reference yield:

: 119336-08-2,79677-59-1
methyl (S)-2-((tert-butoxycarbonyl)amino)-3-(4-hydroxy-3-iodophenyl)propanoate

: 1379654-44-0
C₄₀H₄₈N₆O₉

Guidance literature:: Multi-step reaction with 12 steps

1.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 1 h / 0 °C

1.2: 3 h / 20 °C

2.1: tetrabutylammomium bromide; sodium hydroxide / dichloromethane / 1 h / 20 °C

3.1: trifluoroacetic acid / chloroform / 1 h / 0 °C

4.1: 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 1 h / 0 °C

4.2: 96 h / 20 °C

5.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / methanol; water; toluene / 2 h / 90 °C

6.1: tetrabutylammonium hydrogen sulfate / dichloromethane / 2 h / 20 °C

7.1: trifluoroacetic acid / chloroform / 1 h / 0 °C

8.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-hydroxy-3,4-dihydrobenzotriazine-4-one / tetrahydrofuran / 72 h / 0 - 20 °C / Inert atmosphere

9.1: lithium hydroxide monohydrate; dihydrogen peroxide / methanol / 1 h / 0 °C

9.2: 22 h / 20 °C

10.1: trifluoroacetic acid / chloroform / 2 h / 0 °C

11.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-hydroxy-3,4-dihydrobenzotriazine-4-one / N,N-dimethyl-formamide / 1 h / 0 °C

11.2: 96 h / 20 °C

12.1: palladium 10% on activated carbon / ethanol; cyclohexa-1,4-diene / 168 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; palladium 10% on activated carbon; tetrabutylammomium bromide; dihydrogen peroxide; sodium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; 3-hydroxy-3,4-dihydrobenzotriazine-4-one; triphenylphosphine; tetrabutylammonium hydrogen sulfate; trifluoroacetic acid; sodium hydroxide; diethylazodicarboxylate; In tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; cyclohexa-1,4-diene; water; N,N-dimethyl-formamide; toluene; 5.1: Suzuki coupling;
DOI:10.1002/chem.201103185

Reference yield:

: 691394-91-9
methyl (S)-3-(4-(benzyloxy)-3-iodophenyl)-2-((tert-butoxycarbonyl)amino)propanoate

: 1379654-44-0
C₄₀H₄₈N₆O₉

Guidance literature:: Multi-step reaction with 11 steps

1.1: tetrabutylammomium bromide; sodium hydroxide / dichloromethane / 1 h / 20 °C

2.1: trifluoroacetic acid / chloroform / 1 h / 0 °C

3.1: 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / N,N-dimethyl-formamide / 1 h / 0 °C

3.2: 96 h / 20 °C

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / methanol; water; toluene / 2 h / 90 °C

5.1: tetrabutylammonium hydrogen sulfate / dichloromethane / 2 h / 20 °C

6.1: trifluoroacetic acid / chloroform / 1 h / 0 °C

7.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-hydroxy-3,4-dihydrobenzotriazine-4-one / tetrahydrofuran / 72 h / 0 - 20 °C / Inert atmosphere

8.1: lithium hydroxide monohydrate; dihydrogen peroxide / methanol / 1 h / 0 °C

8.2: 22 h / 20 °C

9.1: trifluoroacetic acid / chloroform / 2 h / 0 °C

10.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-hydroxy-3,4-dihydrobenzotriazine-4-one / N,N-dimethyl-formamide / 1 h / 0 °C

10.2: 96 h / 20 °C

11.1: palladium 10% on activated carbon / ethanol; cyclohexa-1,4-diene / 168 h / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; palladium 10% on activated carbon; tetrabutylammomium bromide; dihydrogen peroxide; sodium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; 3-hydroxy-3,4-dihydrobenzotriazine-4-one; tetrabutylammonium hydrogen sulfate; trifluoroacetic acid; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; cyclohexa-1,4-diene; water; N,N-dimethyl-formamide; toluene; 4.1: Suzuki coupling;
DOI:10.1002/chem.201103185