Technology Process of methyl 3,5-dibromo-4-(bis-(tert-butoxycarbonyl)amino)benzoate
There total 1 articles about methyl 3,5-dibromo-4-(bis-(tert-butoxycarbonyl)amino)benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap;
In
dichloromethane;
at 20 ℃;
for 1h;
Inert atmosphere;
DOI:10.1021/ja311729d
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium hydroxide / water; tetrahydrofuran / Inert atmosphere
2.1: 1,1'-carbonyldiimidazole / dichloromethane / Inert atmosphere
2.2: 20 °C / Inert atmosphere
3.1: triethylamine / dichloromethane; dimethyl sulfoxide / 0.33 h / 20 °C / Inert atmosphere
4.1: p-toluenesulfonyl chloride; dmap / dichloromethane / 0.17 h / 20 °C / Inert atmosphere
With
dmap; triethylamine; p-toluenesulfonyl chloride; 1,1'-carbonyldiimidazole; lithium hydroxide;
In
tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide;
DOI:10.1021/ja311729d
- Guidance literature:
-
With
lithium hydroxide;
In
tetrahydrofuran; water;
Inert atmosphere;
DOI:10.1021/ja311729d