N-[3-[[2-(Acetylamino)-2-deoxy-4,6-O-(phenylmethylene)-beta-D-galactopyranosyl]oxy]propyl]-2,2,2-trifluoroacetamide

Base Information

Chemical Name:N-[3-[[2-(Acetylamino)-2-deoxy-4,6-O-(phenylmethylene)-beta-D-galactopyranosyl]oxy]propyl]-2,2,2-trifluoroacetamide
CAS No.:197794-88-0
Molecular Formula:C₂₀H₂₅F₃N₂O₇
Molecular Weight:462.423
Hs Code.:
DSSTox Substance ID:DTXSID501107640

Synonyms:DTXSID501107640;197794-88-0;N-[3-[[2-(Acetylamino)-2-deoxy-4,6-O-(phenylmethylene)-beta-D-galactopyranosyl]oxy]propyl]-2,2,2-trifluoroacetamide

Suppliers and Price of N-[3-[[2-(Acetylamino)-2-deoxy-4,6-O-(phenylmethylene)-beta-D-galactopyranosyl]oxy]propyl]-2,2,2-trifluoroacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[3-[[2-(Acetylamino)-2-deoxy-4,6-O-(phenylmethylene)-beta-D-galactopyranosyl]oxy]propyl]-2,2,2-trifluoroacetamide

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:7
Exact Mass:462.16138563
Heavy Atom Count:32
Complexity:645

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)NC1C(C2C(COC(O2)C3=CC=CC=C3)OC1OCCCNC(=O)C(F)(F)F)O
Isomeric SMILES:CC(=O)N[C@@H]1[C@H]([C@@H]2[C@@H](COC(O2)C3=CC=CC=C3)O[C@H]1OCCCNC(=O)C(F)(F)F)O

Technology Process of N-[3-[[2-(Acetylamino)-2-deoxy-4,6-O-(phenylmethylene)-beta-D-galactopyranosyl]oxy]propyl]-2,2,2-trifluoroacetamide

There total 2 articles about N-[3-[[2-(Acetylamino)-2-deoxy-4,6-O-(phenylmethylene)-beta-D-galactopyranosyl]oxy]propyl]-2,2,2-trifluoroacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1125-88-8
benzaldehyde dimethyl acetal

: 122998-73-6
3-trifluoroacetamidopropyl 2-acetamido-2-deoxy-β-D-galactopyranoside

: 197794-88-0
3-trifluoroacetamidopropyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside

Guidance literature:: With toluene-4-sulfonic acid; In acetonitrile; at 50 ℃; for 1h;

Reference yield:

: (3-trifluoroacetamidopropyl)-2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-galactopyranoside

: 197794-88-0
3-trifluoroacetamidopropyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: NaOMe / methanol

2: 84 percent / p-toluenesulfonic acid / acetonitrile / 1 h / 50 °C

With sodium methylate; toluene-4-sulfonic acid; In methanol; acetonitrile;

Reference yield:

: 197794-88-0
3-trifluoroacetamidopropyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside

: 197794-91-5
3-trifluoroacetamidopropyl 2-acetamido-3-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-α-D-glactopyranosyl)-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Ag₂CO₃, AgClO₄, 4 Angstroem sieves / 1.) CH₂Cl₂, RT, 1 h, 2.) CH₂Cl₂, RT, 24 h

2: 53 percent / H₂ / 10percent Pd/C / methanol / 16 - 48 °C

With 4 A molecular sieve; hydrogen; silver perchlorate; silver carbonate; palladium on activated charcoal; In methanol;