N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine

Base Information

Chemical Name:N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine
CAS No.:79385-72-1
Molecular Formula:C₃₈H₅₃N₅O₉
Molecular Weight:723.867
Hs Code.:

N<sup>α</sup>-benzyloxycarbonyltryptophyl-N<sup>ε</sup>-t-butoxycarbonyl-lysyl-O-t-butylthreonine

Synonyms:N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine

Suppliers and Price of N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine

There total 9 articles about N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 79385-68-5
N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine 2-trimethylsilylethyl ester

: 79385-72-1
N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine

Guidance literature:: With tetraethylammonium fluoride; In N,N-dimethyl-formamide; at 30 ℃; for 0.5h;
DOI:10.1039/P19810002040

Reference yield:

: 2389-60-8
Z-Lys(Boc)-OH

: 79385-72-1
N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine

Guidance literature:: Multi-step reaction with 5 steps

1: dicyclohexylcarbodi-imide / dimethylformamide / 1.) 0 deg C, 1 h, 2.) 10 deg C, 1 h

2: 65 percent / triethylamine / dimethylformamide / 1.) 0 deg C, 1 h, 2.) 8 deg C, 18 h

3: 13.1 g / hydrogen, acetic acid / 10percent palladium-charcoal / propan-2-ol / 16 h / Ambient temperature

4: 65 percent / triethylamine / dimethylformamide / 1.) 0 deg C, 1 h, 2.) 8 deg C, 18 h

5: 80 percent / tetraethylammonium fluoride / dimethylformamide / 0.5 h / 30 °C

With hydrogen; tetraethylammonium fluoride; acetic acid; triethylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1039/P19810002040

Reference yield:

: 65903-67-5
Z-Thr(Bu^t)-OTmse

: 79385-72-1
N^α-benzyloxycarbonyltryptophyl-N^ε-t-butoxycarbonyl-lysyl-O-t-butylthreonine

Guidance literature:: Multi-step reaction with 5 steps

1: hydrogen, acetic acid / 10percent palladium-charcoal / propan-2-ol / 3 h / Ambient temperature

2: 65 percent / triethylamine / dimethylformamide / 1.) 0 deg C, 1 h, 2.) 8 deg C, 18 h

3: 13.1 g / hydrogen, acetic acid / 10percent palladium-charcoal / propan-2-ol / 16 h / Ambient temperature

4: 65 percent / triethylamine / dimethylformamide / 1.) 0 deg C, 1 h, 2.) 8 deg C, 18 h

5: 80 percent / tetraethylammonium fluoride / dimethylformamide / 0.5 h / 30 °C

With hydrogen; tetraethylammonium fluoride; acetic acid; triethylamine; palladium on activated charcoal; In N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1039/P19810002040