5-(4-trifluoromethylphenyl)-3-(2-morpholinoethyl)imino-2-(3-pyridyl)amino-3,5-dihydrophenazine

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Chemical Name:5-(4-trifluoromethylphenyl)-3-(2-morpholinoethyl)imino-2-(3-pyridyl)amino-3,5-dihydrophenazine
CAS No.:1353736-52-3
Molecular Formula:C₃₀H₂₇F₃N₆O
Molecular Weight:544.579
Hs Code.:

Synonyms:5-(4-trifluoromethylphenyl)-3-(2-morpholinoethyl)imino-2-(3-pyridyl)amino-3,5-dihydrophenazine

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Chemical Property of 5-(4-trifluoromethylphenyl)-3-(2-morpholinoethyl)imino-2-(3-pyridyl)amino-3,5-dihydrophenazine

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Technology Process of 5-(4-trifluoromethylphenyl)-3-(2-morpholinoethyl)imino-2-(3-pyridyl)amino-3,5-dihydrophenazine

There total 10 articles about 5-(4-trifluoromethylphenyl)-3-(2-morpholinoethyl)imino-2-(3-pyridyl)amino-3,5-dihydrophenazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.8%

: 2038-03-1
4-(2-AMINOETHYL)MORPHOLINE

: C₂₄H₁₆F₃N₅

: 1353736-52-3
5-(4-trifluoromethylphenyl)-3-(2-morpholinoethyl)imino-2-(3-pyridyl)amino-3,5-dihydrophenazine

Guidance literature:: With acetic acid; In 1,4-dioxane; at 110 ℃;
DOI:10.1021/jm300828h

Reference yield:

: C₁₉H₁₂F₄N₄O₄

: 1353736-52-3
5-(4-trifluoromethylphenyl)-3-(2-morpholinoethyl)imino-2-(3-pyridyl)amino-3,5-dihydrophenazine

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / tetrahydrofuran / Reflux

2: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 20 °C / 2068.65 Torr

3: air / methanol / 20 °C

4: acetic acid / 1,4-dioxane / 110 °C

With palladium 10% on activated carbon; hydrogen; acetic acid; triethylamine; In tetrahydrofuran; 1,4-dioxane; methanol;
DOI:10.1021/jm300828h

Reference yield:

: C₂₄H₁₇F₃N₆O₄

: 1353736-52-3
5-(4-trifluoromethylphenyl)-3-(2-morpholinoethyl)imino-2-(3-pyridyl)amino-3,5-dihydrophenazine

Guidance literature:: Multi-step reaction with 3 steps

1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 20 °C / 2068.65 Torr

2: air / methanol / 20 °C

3: acetic acid / 1,4-dioxane / 110 °C

With palladium 10% on activated carbon; hydrogen; acetic acid; In tetrahydrofuran; 1,4-dioxane; methanol;
DOI:10.1021/jm300828h