[(2R,3R,4R,5S,6S)-6-(2-Azido-ethyl)-4-benzyloxy-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-tert-butyl-dimethyl-silane

Base Information

Chemical Name:[(2R,3R,4R,5S,6S)-6-(2-Azido-ethyl)-4-benzyloxy-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-tert-butyl-dimethyl-silane
CAS No.:511511-38-9
Molecular Formula:C₂₃H₃₉N₃O₅Si
Molecular Weight:465.665
Hs Code.:

Synonyms:[(2R,3R,4R,5S,6S)-6-(2-Azido-ethyl)-4-benzyloxy-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-tert-butyl-dimethyl-silane

Suppliers and Price of [(2R,3R,4R,5S,6S)-6-(2-Azido-ethyl)-4-benzyloxy-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-tert-butyl-dimethyl-silane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [(2R,3R,4R,5S,6S)-6-(2-Azido-ethyl)-4-benzyloxy-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-tert-butyl-dimethyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [(2R,3R,4R,5S,6S)-6-(2-Azido-ethyl)-4-benzyloxy-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-tert-butyl-dimethyl-silane

There total 3 articles about [(2R,3R,4R,5S,6S)-6-(2-Azido-ethyl)-4-benzyloxy-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-tert-butyl-dimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Methanesulfonic acid 2-[(2S,3S,4R,5R,6R)-4-benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-6-methoxymethyl-tetrahydro-pyran-2-yl]-ethyl ester

: 511511-38-9
[(2R,3R,4R,5S,6S)-6-(2-Azido-ethyl)-4-benzyloxy-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-tert-butyl-dimethyl-silane

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 60 ℃; for 3h;
DOI:10.1002/1099-0690(200212)2002:23<3954::AID-EJOC3954>3.0.CO;2-2

Reference yield:

: [(2S,3S,4R,5R,6R)-4-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-6-methoxymethyl-tetrahydro-pyran-2-yl]-acetaldehyde

: 511511-38-9
[(2R,3R,4R,5S,6S)-6-(2-Azido-ethyl)-4-benzyloxy-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-tert-butyl-dimethyl-silane

Guidance literature:: Multi-step reaction with 3 steps

1: 0.952 g / LiAlH₄ / tetrahydrofuran / 0.5 h

2: pyridine / CH₂Cl₂ / 16 h

3: NaN₃ / dimethylformamide / 3 h / 60 °C

With pyridine; lithium aluminium tetrahydride; sodium azide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/1099-0690(200212)2002:23<3954::AID-EJOC3954>3.0.CO;2-2

Reference yield:

: 511511-37-8
2-[(2S,3S,4R,5R,6R)-4-Benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-6-methoxymethyl-tetrahydro-pyran-2-yl]-ethanol

: 511511-38-9
[(2R,3R,4R,5S,6S)-6-(2-Azido-ethyl)-4-benzyloxy-5-methoxy-2-methoxymethyl-tetrahydro-pyran-3-yloxy]-tert-butyl-dimethyl-silane

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / CH₂Cl₂ / 16 h

2: NaN₃ / dimethylformamide / 3 h / 60 °C

With pyridine; sodium azide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/1099-0690(200212)2002:23<3954::AID-EJOC3954>3.0.CO;2-2