phenyl 2,6-di-O-benzyl-3,4-di-O-di-(tri-isopropyl-silyl)-1-thio-β-D-glucopyranoside

Base Information

• Chemical Name: phenyl 2,6-di-O-benzyl-3,4-di-O-di-(tri-isopropyl-silyl)-1-thio-β-D-glucopyranoside
• CAS No.: 947256-92-0
• Molecular Formula: C₄₄H₆₈O₅SSi₂
• Molecular Weight: 765.258

Synonyms:phenyl 2,6-di-O-benzyl-3,4-di-O-di-(tri-isopropyl-silyl)-1-thio-β-D-glucopyranoside

Chemical Property of phenyl 2,6-di-O-benzyl-3,4-di-O-di-(tri-isopropyl-silyl)-1-thio-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 2,6-di-O-benzyl-3,4-di-O-di-(tri-isopropyl-silyl)-1-thio-β-D-glucopyranoside

There total 5 articles about phenyl 2,6-di-O-benzyl-3,4-di-O-di-(tri-isopropyl-silyl)-1-thio-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

phenyl 2,6-di-O-benzyl-1-thio-β-D-glucopyranoside (864966-93-8) + triisopropylsilyl chloride (13154-24-0) → phenyl 2,6-di-O-benzyl-3,4-di-O-di-(tri-isopropyl-silyl)-1-thio-β-D-glucopyranoside (947256-92-0)

Guidance literature:

With 2,6-dimethylpyridine; silver trifluoromethanesulfonate; In N,N-dimethyl-formamide; at 60 ℃;

DOI:10.1021/ja071955l

Reference yield:

benzaldehyde dimethyl acetal (1125-88-8) → phenyl 2,6-di-O-benzyl-3,4-di-O-di-(tri-isopropyl-silyl)-1-thio-β-D-glucopyranoside (947256-92-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: butane-2,3-dione; HC(OMe)3 / methanol

1.2: NaH / dimethylformamide

1.3: HCl; H₂O / Heating

2.1: 88 percent / 2,6-lutidine; AgOTf / dimethylformamide / 60 °C

With 2,6-dimethylpyridine; silver trifluoromethanesulfonate; trimethyl orthoformate; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/ja071955l

Reference yield:

(2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-phenylsulfanyl-tetrahydro-pyran-3,4,5-triol (2936-70-1,5624-48-6,13992-15-9,16758-34-2,28244-97-5,77481-62-0,77481-63-1,105088-17-3,149495-84-1) → phenyl 2,6-di-O-benzyl-3,4-di-O-di-(tri-isopropyl-silyl)-1-thio-β-D-glucopyranoside (947256-92-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: butane-2,3-dione; HC(OMe)3 / methanol

1.2: NaH / dimethylformamide

1.3: HCl; H₂O / Heating

2.1: 88 percent / 2,6-lutidine; AgOTf / dimethylformamide / 60 °C

With 2,6-dimethylpyridine; silver trifluoromethanesulfonate; trimethyl orthoformate; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/ja071955l

upstream raw materials:

phenyl 2,6-di-O-benzyl-1-thio-β-D-glucopyranoside

triisopropylsilyl chloride

benzaldehyde dimethyl acetal

(2R,3S,4S,5R,6S)-2-Hydroxymethyl-6-phenylsulfanyl-tetrahydro-pyran-3,4,5-triol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 947256-92-0 phenyl 2,6-di-O-benzyl-3,4-di-O-di-(tri-isopropyl-silyl)-1-thio-β-D-glucopyranoside

Send

Send

Metric Ton KG G Pound L ML

Send

Send