4-(((3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f ][1,4]thiazepin-8-yl)oxy)-butanoic acid

Base Information

• Chemical Name: 4-(((3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f ][1,4]thiazepin-8-yl)oxy)-butanoic acid
• CAS No.: 1443039-34-6
• Molecular Formula: C₂₆H₃₅NO₆S
• Molecular Weight: 489.633

Synonyms:4-(((3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f ][1,4]thiazepin-8-yl)oxy)-butanoic acid

Chemical Property of 4-(((3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f ][1,4]thiazepin-8-yl)oxy)-butanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(((3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f ][1,4]thiazepin-8-yl)oxy)-butanoic acid

There total 3 articles about 4-(((3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f ][1,4]thiazepin-8-yl)oxy)-butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

C30H43NO6S (1443039-51-7) → 4-(((3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f ][1,4]thiazepin-8-yl)oxy)-butanoic acid (1443039-34-6)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 25 ℃; for 2h;

DOI:10.1021/jm400459m

Reference yield:

(3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-5-phenyl-1,4-benzothiazepine-8-ol 1,1-dioxide → 4-(((3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f ][1,4]thiazepin-8-yl)oxy)-butanoic acid (1443039-34-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 2 h / 100 °C

2: hydrogenchloride / 1,4-dioxane / 2 h / 25 °C

With hydrogenchloride; potassium carbonate; In 1,4-dioxane; dimethyl sulfoxide;

DOI:10.1021/jm400459m

Reference yield:

(3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7,8-dimethoxy-5-phenyl-1-4-benzothiazepine-1,1-dioxide → 4-(((3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f ][1,4]thiazepin-8-yl)oxy)-butanoic acid (1443039-34-6)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride; aluminum (III) chloride / 1,2-dichloro-ethane / 2.5 h / 25 °C

2: potassium carbonate / dimethyl sulfoxide / 2 h / 100 °C

3: hydrogenchloride / 1,4-dioxane / 2 h / 25 °C

With hydrogenchloride; aluminum (III) chloride; potassium carbonate; In 1,4-dioxane; dimethyl sulfoxide; 1,2-dichloro-ethane;

DOI:10.1021/jm400459m

upstream raw materials:

C₃₀H₄₃NO₆S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1443039-34-6 4-(((3R,5R)-3-butyl-3-ethyl-7-methoxy-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydrobenzo[f ][1,4]thiazepin-8-yl)oxy)-butanoic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send