Technology Process of C32H46O5Si
There total 6 articles about C32H46O5Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
N-chloro-succinimide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrabutyl-ammonium chloride; sodium hydrogencarbonate; potassium carbonate;
In
dichloromethane;
at 20 ℃;
Inert atmosphere;
DOI:10.1021/ol300390k
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: tert.-butyl lithium / tetrahydrofuran / 0.17 h / -78 °C / Inert atmosphere
1.2: brine
2.1: Burgess Reagent / tetrahydrofuran / 20 - 50 °C / Inert atmosphere
3.1: dichloromethane / 0.33 h / 0 °C / Inert atmosphere
4.1: sodium hydroxide / methanol; water / 0.33 h / 20 °C
5.1: N-chloro-succinimide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrabutyl-ammonium chloride; sodium hydrogencarbonate; potassium carbonate / dichloromethane / 20 °C / Inert atmosphere
With
N-chloro-succinimide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; Burgess Reagent; tetrabutyl-ammonium chloride; tert.-butyl lithium; sodium hydrogencarbonate; potassium carbonate; sodium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; water;
1.1: Barbier type cyclization;
DOI:10.1021/ol300390k
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dichloromethane / 0.33 h / 0 °C / Inert atmosphere
2: sodium hydroxide / methanol; water / 0.33 h / 20 °C
3: N-chloro-succinimide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrabutyl-ammonium chloride; sodium hydrogencarbonate; potassium carbonate / dichloromethane / 20 °C / Inert atmosphere
With
N-chloro-succinimide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; tetrabutyl-ammonium chloride; sodium hydrogencarbonate; potassium carbonate; sodium hydroxide;
In
methanol; dichloromethane; water;
DOI:10.1021/ol300390k