2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile

Base Information

Chemical Name:2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile
CAS No.:1201643-83-5
Molecular Formula:C₁₈H₁₇BrN₂O
Molecular Weight:357.25
Hs Code.:

Synonyms:2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile

Suppliers and Price of 2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile

There total 10 articles about 2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1201643-82-4
N-(4-bromo-2-(2-(4-(2-cyanopropan-2-yl)phenyl)acetyl)phenyl)formamide

: 1201643-83-5
2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile

Guidance literature:: With hydrogenchloride; In acetone; for 24h;

Reference yield:

: 10075-50-0
5-bromo-1H-indole

: 1201643-83-5
2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydride / dimethyl sulfoxide / 0.5 h / 0 °C

1.2: 0 - 20 °C

2.1: aluminum (III) chloride / dichloromethane / 0.17 h / 25 °C

2.2: 25 °C

3.1: sodium tetrahydroborate; trifluoroacetic acid / dichloromethane / 0 - 25 °C / Inert atmosphere

4.1: caesium carbonate / tetrahydrofuran; methanol / 2 h / 70 °C

5.1: ozone / N,N-dimethyl-formamide / 0.13 h / -5 °C

6.1: hydrogenchloride / acetone / 24 h

With hydrogenchloride; aluminum (III) chloride; sodium tetrahydroborate; sodium hydride; caesium carbonate; ozone; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;

Reference yield:

: 4-(1-cyano-1-methylethyl)benzoic acid chloride

: 1201643-83-5
2-(4-(2-(2-amino-5-bromophenyl)-2-oxoethyl)phenyl)-2-methylpropanenitrile

Guidance literature:: Multi-step reaction with 5 steps

1.1: aluminum (III) chloride / dichloromethane / 0.17 h / 25 °C

1.2: 25 °C

2.1: sodium tetrahydroborate; trifluoroacetic acid / dichloromethane / 0 - 25 °C / Inert atmosphere

3.1: caesium carbonate / tetrahydrofuran; methanol / 2 h / 70 °C

4.1: ozone / N,N-dimethyl-formamide / 0.13 h / -5 °C

5.1: hydrogenchloride / acetone / 24 h

With hydrogenchloride; aluminum (III) chloride; sodium tetrahydroborate; caesium carbonate; ozone; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetone;