Carbamic acid, (2-aminophenyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-

Base Information

Chemical Name:Carbamic acid, (2-aminophenyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-
CAS No.:123259-35-8
Molecular Formula:C₁₅H₂₁N₃O₂
Molecular Weight:275.351
Hs Code.:
DSSTox Substance ID:DTXSID101131467

Synonyms:DTXSID101131467;Carbamic acid, (2-aminophenyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-;123259-35-8

Suppliers and Price of Carbamic acid, (2-aminophenyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbamic acid, (2-aminophenyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:275.16337692
Heavy Atom Count:20
Complexity:349

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1C2CCC1CC(C2)OC(=O)NC3=CC=CC=C3N
Isomeric SMILES:CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)NC3=CC=CC=C3N

Technology Process of Carbamic acid, (2-aminophenyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-

There total 4 articles about Carbamic acid, (2-aminophenyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 123259-36-9
endo-8-methyl-8-azabicyclo<3.2.1>oct-3-yl N-(2-nitrophenyl)carbamate hydrochloride

: 123259-35-8
endo-8-methyl-8-azabicyclo<3.2.1>oct-3-yl N-(2-aminophenyl)carbamate

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; water; under 760 Torr; Ambient temperature;
DOI:10.1021/jm00170a009

Reference yield:

: 2292-08-2
tropine hydrochloride

: 123259-35-8
endo-8-methyl-8-azabicyclo<3.2.1>oct-3-yl N-(2-aminophenyl)carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / acetonitrile / 1.) O deg C, 30 min, 2.) RT, 24 h

2: 6.5 g / pyridine / 4 h / 80 °C

3: 4.4 g / H₂ / 10percent Pd/C / ethanol; H₂O / 760 Torr / Ambient temperature

With hydrogen; palladium on activated charcoal; In pyridine; ethanol; water; acetonitrile;
DOI:10.1021/jm00170a009

Reference yield:

: 123259-23-4
endo-8-methyl-8-azabicyclo<3.2.1>oct-3-yl chloroformate hydrochloride

: 123259-35-8
endo-8-methyl-8-azabicyclo<3.2.1>oct-3-yl N-(2-aminophenyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 6.5 g / pyridine / 4 h / 80 °C

2: 4.4 g / H₂ / 10percent Pd/C / ethanol; H₂O / 760 Torr / Ambient temperature

With hydrogen; palladium on activated charcoal; In pyridine; ethanol; water;
DOI:10.1021/jm00170a009