1--2-fluorobenzene

Base Information

Chemical Name:1--2-fluorobenzene
CAS No.:82374-07-0
Molecular Formula:C₁₀H₁₁ClFN
Molecular Weight:199.655
Hs Code.:

1-<chloro(isopropylimino)methyl>-2-fluorobenzene

Synonyms:1--2-fluorobenzene

Suppliers and Price of 1--2-fluorobenzene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1--2-fluorobenzene

Chemical Property:

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Technology Process of 1--2-fluorobenzene

There total 1 articles about 1--2-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 64141-89-5
o-fluoro-N-isopropylbenzamide

: 82374-07-0
1--2-fluorobenzene

Guidance literature:: With thionyl chloride; for 0.75h;
DOI:10.1021/jo00140a013

Reference yield:

: 82374-07-0
1--2-fluorobenzene

: 81537-96-4
5-chloro-2-phenyl>-2'-fluorobenzophenone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-butyllithium / 1.) 0 deg C, 25 h, ether/hexane, 2.) -12 to -5 deg C, 20 h

With n-butyllithium;
DOI:10.1021/jo00140a013

Reference yield:

: 82374-07-0
1--2-fluorobenzene

: 81537-93-1
9-chloro-7-(o-fluorophenyl)-5H-dibenzazepine

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) n-butyllithium / 1.) 0 deg C, 25 h, ether/hexane, 2.) -12 to -5 deg C, 20 h

3: 1.) CNBr, 2.) NH₃ / 1.) CH₂Cl₂, 0 to 5 deg C, 2 h, 2.) THF, ethanol, RT, overnight

With n-butyllithium; bromocyane; ammonia;
DOI:10.1021/jo00140a013