Methyl 5-chloro-2-fluoro-3-nitrobenzoate

Base Information

Chemical Name:Methyl 5-chloro-2-fluoro-3-nitrobenzoate
CAS No.:1153285-33-6
Molecular Formula:C₈H₅ClFNO₄
Molecular Weight:233.583
Hs Code.:
European Community (EC) Number:861-401-1

Synonyms:methyl 5-chloro-2-fluoro-3-nitrobenzoate;1153285-33-6;SCHEMBL1462927;HZXZBFRZKGKBFX-UHFFFAOYSA-N;methyl5-chloro-2-fluoro-3-nitrobenzoate;EN300-99941;E86847;A1-22909

Suppliers and Price of Methyl 5-chloro-2-fluoro-3-nitrobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Methyl 5-chloro-2-fluoro-3-nitrobenzoate

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:232.9891135
Heavy Atom Count:15
Complexity:270

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=C(C(=CC(=C1)Cl)[N+](=O)[O-])F

Technology Process of Methyl 5-chloro-2-fluoro-3-nitrobenzoate

There total 1 articles about Methyl 5-chloro-2-fluoro-3-nitrobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 57381-36-9
methyl 5-chloro-2-fluorobenzoatone

: 1153285-33-6
methyl 5-chloro-2-fluoro-3-nitrobenzoate

Guidance literature:: With sulfuric acid; nitric acid; In water; at 0 - 20 ℃; for 3h;

Reference yield: 63.0%

: 1153285-33-6
methyl 5-chloro-2-fluoro-3-nitrobenzoate

: 1269421-13-7
3-amino-5-chloro-2-fluorobenzoic acid methyl ester

Guidance literature:: methyl 5-chloro-2-fluoro-3-nitrobenzoate; With iron; ammonium chloride; In ethanol; water; at 85 ℃; for 2h;

With sodium hydrogencarbonate; In ethanol; water; ethyl acetate; at 20 ℃;

Reference yield:

: 1153285-33-6
methyl 5-chloro-2-fluoro-3-nitrobenzoate

: C₁₁H₁₃ClFNO₄S

Guidance literature:: Multi-step reaction with 2 steps

1.1: ammonium chloride; iron / ethanol; water / 2 h / 85 °C

1.2: 20 °C

2.1: triethylamine / tetrahydrofuran / 1.5 h / 0 °C

With iron; ammonium chloride; triethylamine; In tetrahydrofuran; ethanol; water;