1,1-Dioxo-4-phenyl-1,4-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-ylamine

Base Information

• Chemical Name: 1,1-Dioxo-4-phenyl-1,4-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-ylamine
• CAS No.: 108221-77-8
• Molecular Formula: C₁₃H₁₁N₃O₂S
• Molecular Weight: 273.315
• Mol file: 108221-77-8.mol

Synonyms:1,1-Dioxo-4-phenyl-1,4-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-ylamine

Chemical Property of 1,1-Dioxo-4-phenyl-1,4-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-ylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-Dioxo-4-phenyl-1,4-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-ylamine

There total 1 articles about 1,1-Dioxo-4-phenyl-1,4-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3-chloro-4-phenyl 4H-1,2,4-benzothiadiazine 1,1-dioxide (107089-78-1) → 1,1-Dioxo-4-phenyl-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-ylamine (108221-77-8)

Guidance literature:

With ammonium hydroxide; In chloroform; for 0.0833333h; Ambient temperature;

DOI:10.1055/s-1986-31810

Reference yield: 92.0%

1,1-Dioxo-4-phenyl-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-ylamine (108221-77-8) + diethyl 2-ethoxymethylenemalonate (87-13-8) → 2-[(1,1-Dioxo-4-phenyl-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-ylamino)-methylene]-malonic acid diethyl ester (123705-14-6)

Guidance literature:

at 170 - 180 ℃; for 2h;

Reference yield:

1,1-Dioxo-4-phenyl-1,4-dihydro-1λ6-benzo[1,2,4]thiadiazin-3-ylamine (108221-77-8) → 4,10,10-Trioxo-9-phenyl-9,10-dihydro-4H-10λ6-thia-1,4a,9-triaza-anthracene-3-carboxylic acid ethyl ester (123705-17-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / 2 h / 170 - 180 °C

2: 75 percent / dowtherm A / 8 h / 200 - 210 °C

With diphenyl ether-biphenyl eutectic;

upstream raw materials:

3-chloro-4-phenyl 4H-1,2,4-benzothiadiazine 1,1-dioxide

Downstream raw materials:

2-[(1,1-Dioxo-4-phenyl-1,4-dihydro-1λ⁶-benzo[1,2,4]thiadiazin-3-ylamino)-methylene]-malonic acid diethyl ester

4,10,10-Trioxo-9-phenyl-9,10-dihydro-4H-10λ⁶-thia-1,4a,9-triaza-anthracene-3-carboxylic acid ethyl ester