N_δ-Boc-N_α-[(2R)-1-(3-benzylureido)-3-phenylpropan-2-yl]ornithine benzyl amide

Base Information

Chemical Name:N_δ-Boc-N_α-[(2R)-1-(3-benzylureido)-3-phenylpropan-2-yl]ornithine benzyl amide
CAS No.:1416442-26-6
Molecular Formula:C₃₄H₄₅N₅O₄
Molecular Weight:587.762
Hs Code.:

N<sub>δ</sub>-Boc-N<sub>α</sub>-[(2R)-1-(3-benzylureido)-3-phenylpropan-2-yl]ornithine benzyl amide

Synonyms:N_δ-Boc-N_α-[(2R)-1-(3-benzylureido)-3-phenylpropan-2-yl]ornithine benzyl amide

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Chemical Property of N_δ-Boc-N_α-[(2R)-1-(3-benzylureido)-3-phenylpropan-2-yl]ornithine benzyl amide

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Technology Process of N_δ-Boc-N_α-[(2R)-1-(3-benzylureido)-3-phenylpropan-2-yl]ornithine benzyl amide

There total 2 articles about N_δ-Boc-N_α-[(2R)-1-(3-benzylureido)-3-phenylpropan-2-yl]ornithine benzyl amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 1416442-06-2
N_δ-Boc-N_α-[(2R)-3-phenyl-1-(Fmoc)amino-propan-2-yl]ornithine benzyl amide

: 3173-56-6
benzyl isothiocyanate

: 1416442-26-6
N_δ-Boc-N_α-[(2R)-1-(3-benzylureido)-3-phenylpropan-2-yl]ornithine benzyl amide

Guidance literature:: N_δ-Boc-N_α-[(2R)-3-phenyl-1-(Fmoc)amino-propan-2-yl]ornithine benzyl amide; With diethylamine; In dichloromethane; at 20 ℃; for 2h;

benzyl isothiocyanate; In dichloromethane; at 0 ℃;
DOI:10.1016/j.ejmech.2012.10.015

Reference yield:

: C₂₆H₃₄N₄O₃

: 1416442-26-6
N_δ-Boc-N_α-[(2R)-1-(3-benzylureido)-3-phenylpropan-2-yl]ornithine benzyl amide

Guidance literature:: Multi-step reaction with 2 steps

1.1: methanol / 0.08 h / Reflux

1.2: 2 h

2.1: diethylamine / dichloromethane / 2 h / 20 °C

2.2: 0 °C

With diethylamine; In methanol; dichloromethane;
DOI:10.1016/j.ejmech.2012.10.015