methyl (1S,5R)-1-(4-methoxybenzyl)-2-oxo-5-phenylcycloheptanecarboxylate

Base Information

Chemical Name:methyl (1S,5R)-1-(4-methoxybenzyl)-2-oxo-5-phenylcycloheptanecarboxylate
CAS No.:1310218-24-6
Molecular Formula:C₂₃H₂₆O₄
Molecular Weight:366.457
Hs Code.:

Synonyms:methyl (1S,5R)-1-(4-methoxybenzyl)-2-oxo-5-phenylcycloheptanecarboxylate

Suppliers and Price of methyl (1S,5R)-1-(4-methoxybenzyl)-2-oxo-5-phenylcycloheptanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (1S,5R)-1-(4-methoxybenzyl)-2-oxo-5-phenylcycloheptanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (1S,5R)-1-(4-methoxybenzyl)-2-oxo-5-phenylcycloheptanecarboxylate

There total 2 articles about methyl (1S,5R)-1-(4-methoxybenzyl)-2-oxo-5-phenylcycloheptanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 4894-75-1
1-phenyl-4-cyclohexanone

: 1186002-27-6
methyl α-(4-methoxybenzyl)diazoacetate

: 1310218-24-6
methyl (1S,5R)-1-(4-methoxybenzyl)-2-oxo-5-phenylcycloheptanecarboxylate

Guidance literature:: With trimethylaluminum; (S)-3-3’-bis(trimethylsilyl-1,1’-binaphthyl)-2,2’-diol; In toluene; at -60 ℃; for 24h; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ja202070j

Reference yield:

: methyl 2-(4-methoxybenzyl)-3-oxobutanoate

: 1310218-24-6
methyl (1S,5R)-1-(4-methoxybenzyl)-2-oxo-5-phenylcycloheptanecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 4-acetamidobenzenesulfonyl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 12 h / 0 - 20 °C

2: trimethylaluminum; (S)-3-3’-bis(trimethylsilyl-1,1’-binaphthyl)-2,2’-diol / toluene / 24 h / -60 °C / Inert atmosphere

With 4-acetamidobenzenesulfonyl azide; trimethylaluminum; 1,8-diazabicyclo[5.4.0]undec-7-ene; (S)-3-3’-bis(trimethylsilyl-1,1’-binaphthyl)-2,2’-diol; In toluene; acetonitrile;
DOI:10.1021/ja202070j