3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanamide

Base Information

Chemical Name:3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanamide
CAS No.:1215283-04-7
Molecular Formula:C₃₂H₃₆N₄O₅
Molecular Weight:556.662
Hs Code.:

Synonyms:3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanamide

Suppliers and Price of 3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanamide

There total 5 articles about 3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 1215283-05-8
3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanoic acid

: 1215283-04-7
3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanamide

Guidance literature:: With pyridine; di-tert-butyl dicarbonate; ammonium carbonate; In N,N-dimethyl-formamide; for 0.5h;

Reference yield:

: 1215284-41-5
methyl 3-[1-(2,2-dimethylpropanoyl)-7-hydroxy-3-(4-methoxybenzoyl)indolizin-2-yl]-2,2-dimethylpropanoate

: 1215283-04-7
3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanamide

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / N,N-dimethyl-formamide / 6 h / 70 °C

2: hydrazine / ethanol / 2 h / 70 °C

3: sodium hydroxide; water / tetrahydrofuran; methanol / 3 h / 70 °C

4: pyridine; di-tert-butyl dicarbonate; ammonium carbonate / N,N-dimethyl-formamide / 0.5 h

With pyridine; di-tert-butyl dicarbonate; water; ammonium carbonate; potassium carbonate; sodium hydroxide; hydrazine; In tetrahydrofuran; methanol; ethanol; N,N-dimethyl-formamide;

Reference yield:

: methyl 3-[1-(2,2-dimethylpropanoyl)-7-{[6-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)pyridin-2-yl]methoxy}-3-(4-methoxybenzoyl)indolizin-2-yl]-2,2-dimethylpropanoate

: 1215283-04-7
3-{7-[(6-aminopyridin-2-yl)methoxy]-1-(2,2-dimethylpropanoyl)-3-(4-methoxybenzoyl)indolizin-2-yl}-2,2-dimethylpropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine / ethanol / 2 h / 70 °C

2: sodium hydroxide; water / tetrahydrofuran; methanol / 3 h / 70 °C

3: pyridine; di-tert-butyl dicarbonate; ammonium carbonate / N,N-dimethyl-formamide / 0.5 h

With pyridine; di-tert-butyl dicarbonate; water; ammonium carbonate; sodium hydroxide; hydrazine; In tetrahydrofuran; methanol; ethanol; N,N-dimethyl-formamide;