4-Bromo-6-methyl-2-(2-propen-1-yl)-3-pyridinyl 4-chlorobenzenesulfonate

Base Information

Chemical Name:4-Bromo-6-methyl-2-(2-propen-1-yl)-3-pyridinyl 4-chlorobenzenesulfonate
CAS No.:934965-68-1
Molecular Formula:C₁₅H₁₃BrClNO₃S
Molecular Weight:402.696
Hs Code.:
DSSTox Substance ID:DTXSID701151667

Synonyms:DTXSID701151667;4-Bromo-6-methyl-2-(2-propen-1-yl)-3-pyridinyl 4-chlorobenzenesulfonate;934965-68-1

Suppliers and Price of 4-Bromo-6-methyl-2-(2-propen-1-yl)-3-pyridinyl 4-chlorobenzenesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Bromo-6-methyl-2-(2-propen-1-yl)-3-pyridinyl 4-chlorobenzenesulfonate

Chemical Property:

XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:400.94880
Heavy Atom Count:22
Complexity:474

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C(=N1)CC=C)OS(=O)(=O)C2=CC=C(C=C2)Cl)Br

Technology Process of 4-Bromo-6-methyl-2-(2-propen-1-yl)-3-pyridinyl 4-chlorobenzenesulfonate

There total 2 articles about 4-Bromo-6-methyl-2-(2-propen-1-yl)-3-pyridinyl 4-chlorobenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 934965-65-8
4-bromo-2-iodo-6-methylpyridin-3-yl 4-chlorobenznesulfonate

: 106-95-6
allyl bromide

: 934965-68-1
2-allyl-4-bromo-6-methylpyridin-3-yl 4-chlorobenzenesulfonate

Guidance literature:: 4-bromo-2-iodo-6-methylpyridin-3-yl 4-chlorobenznesulfonate; With isopropylmagnesium chloride; In tetrahydrofuran; at -78 ℃; for 0.5h;

allyl bromide; In tetrahydrofuran; at 20 ℃; for 1h;
DOI:10.1016/j.tet.2007.01.027

Reference yield:

: 934965-61-4
2,4-diiodo-6-methylpyridin-3-yl 4-chlorobenzenesulfonate

: 934965-68-1
2-allyl-4-bromo-6-methylpyridin-3-yl 4-chlorobenzenesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1.1: i-PrMgCl / tetrahydrofuran / 0.5 h / -78 °C

1.2: 67 percent / 1,2-dibromotetrafluoroethane / tetrahydrofuran / 6 h / -78 - 20 °C

2.1: i-PrMgCl / tetrahydrofuran / 0.5 h / -78 °C

2.2: 55 percent / tetrahydrofuran / 1 h / 20 °C

With isopropylmagnesium chloride; In tetrahydrofuran;
DOI:10.1016/j.tet.2007.01.027