[4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanol

Base Information

• Chemical Name: [4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanol
• CAS No.: 170939-61-4
• Molecular Formula: C₁₇H₁₂Cl₃NO
• Molecular Weight: 352.647
• Mol file: 170939-61-4.mol

Synonyms:[4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanol

Chemical Property of [4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of [4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanol

There total 2 articles about [4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

[4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanone (170939-26-1) → [4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanol (170939-61-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Ambient temperature;

DOI:10.1021/jm00021a011

Reference yield:

RL3105 (166824-09-5) → [4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanol (170939-61-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 41 percent / NaH / dimethylsulfoxide; diethyl ether / 0.08 h / Ambient temperature

2: 100 percent / LiAlH₄ / tetrahydrofuran / 2 h / Ambient temperature

With lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; diethyl ether; dimethyl sulfoxide;

DOI:10.1021/jm00021a011

Reference yield: 54.0%

1,1'-Carbonyl-di-(1,2,4-triazole) (41864-22-6) + [4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanol (170939-61-4) → 4-[[4-(4-chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methyl]-4H-[1,2,4]triazole + 1-[[4-(4-chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methyl]-1H-[1,2,4]triazole

Guidance literature:

In acetonitrile; at 20 ℃; for 3.5h;

DOI:10.1021/jm011087h

upstream raw materials:

[4-(4-Chloro-phenyl)-1H-pyrrol-3-yl]-(2,4-dichloro-phenyl)-methanone

RL₃₁₀₅