N-(benzyloxycarbonyl)-N'-heptadecylcarbamoyloxymethylbis(hydroxymethyl)aminomethane

Base Information

• Chemical Name: N-(benzyloxycarbonyl)-N'-heptadecylcarbamoyloxymethylbis(hydroxymethyl)aminomethane
• CAS No.: 420107-85-3
• Molecular Formula: C₃₀H₅₂N₂O₆
• Molecular Weight: 536.753
• Mol file: 420107-85-3.mol

Synonyms:N-(benzyloxycarbonyl)-N'-heptadecylcarbamoyloxymethylbis(hydroxymethyl)aminomethane

Chemical Property of N-(benzyloxycarbonyl)-N'-heptadecylcarbamoyloxymethylbis(hydroxymethyl)aminomethane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(benzyloxycarbonyl)-N'-heptadecylcarbamoyloxymethylbis(hydroxymethyl)aminomethane

There total 6 articles about N-(benzyloxycarbonyl)-N'-heptadecylcarbamoyloxymethylbis(hydroxymethyl)aminomethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

5-N-(benzyloxycarbonyl)amino-5-N'-heptadecylcarbamoyloxymethyl-2,2-dimethyl-1,3-dioxane (420107-82-0) → N-(benzyloxycarbonyl)-N'-heptadecylcarbamoyloxymethylbis(hydroxymethyl)aminomethane (420107-85-3)

Guidance literature:

With Montmorillonite K₁₀; In dichloromethane;

DOI:10.1039/b104958p

Reference yield:

heptadecyl isocyanate (7418-01-1) → N-(benzyloxycarbonyl)-N'-heptadecylcarbamoyloxymethylbis(hydroxymethyl)aminomethane (420107-85-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / diazabicyclooctane / toluene / 6 h / pH 8 - 9 / Heating

2: 92 percent / montmorillonite K₁₀ / CH₂Cl₂

With 1,4-diaza-bicyclo[2.2.2]octane; Montmorillonite K₁₀; In dichloromethane; toluene;

DOI:10.1039/b104958p

Reference yield:

benzyl chloroformate (501-53-1,94274-21-2) → N-(benzyloxycarbonyl)-N'-heptadecylcarbamoyloxymethylbis(hydroxymethyl)aminomethane (420107-85-3)

Guidance literature:

Multi-step reaction with 4 steps

1: NaOH / acetonitrile; H₂O

2: APTS / CH₂Cl₂

3: 92 percent / diazabicyclooctane / toluene / 6 h / pH 8 - 9 / Heating

4: 92 percent / montmorillonite K₁₀ / CH₂Cl₂

With 1,4-diaza-bicyclo[2.2.2]octane; sodium hydroxide; Montmorillonite K₁₀; 8-aminopyrene-1,3,6-trisulfonic acid, trisodium salt; In dichloromethane; water; toluene; acetonitrile;

DOI:10.1039/b104958p

upstream raw materials:

5-N-(benzyloxycarbonyl)amino-5-N'-heptadecylcarbamoyloxymethyl-2,2-dimethyl-1,3-dioxane

heptadecyl isocyanate

benzyl chloroformate

benzyl 1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl carbamate

Downstream raw materials:

N-(benzyloxycarbonyl)-N'-heptadecylcarbamoyloxymethylbis[O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)hydroxymethyl]aminomethane