2,3,3,3-Tetrafluoro-2-methoxypropanamide

Base Information

• Chemical Name: 2,3,3,3-Tetrafluoro-2-methoxypropanamide
• CAS No.: 10186-65-9
• Molecular Formula: C₄H₅F₄NO₂
• Molecular Weight: 175.083
• Hs Code.: 2924199090
• European Community (EC) Number: 688-615-6
• DSSTox Substance ID: DTXSID70384344
• Mol file: 10186-65-9.mol

Synonyms:2,3,3,3-tetrafluoro-2-methoxypropanamide;2-Methoxytetrafluoropropionamide;10186-65-9;2-Methoxytetrafluoropropanamide;Maybridge1_002142;SCHEMBL14530109;HMS547J08;DTXSID70384344;DMDUFSAURLOQDT-UHFFFAOYSA-N;AKOS001031715;AKOS016874799;CS-0292761;FT-0691347;Z56761672

Chemical Property of 2,3,3,3-Tetrafluoro-2-methoxypropanamide

Chemical Property:

• Vapor Pressure: 0.502mmHg at 25°C
• Refractive Index: 1.348
• Boiling Point: 191.9°C at 760 mmHg
• Flash Point: 69.9°C
• PSA: 52.32000
• Density: 1.416g/cm³
• LogP: 1.04650
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 175.02564105
• Heavy Atom Count: 11
• Complexity: 168

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Methoxytetrafluoropropionamide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(C(=O)N)(C(F)(F)F)F

Technology Process of 2,3,3,3-Tetrafluoro-2-methoxypropanamide

There total 2 articles about 2,3,3,3-Tetrafluoro-2-methoxypropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-fluoro-2-methoxy trifluoropropanoic acid methyl ester (10186-63-7) → 2.3.3.3-Tetrafluor-2-methoxy-propionsaeureamid (10186-65-9)

Guidance literature:

With ammonium hydroxide;

Reference yield:

→ 2.3.3.3-Tetrafluor-2-methoxy-propionsaeureamid (10186-65-9)

Guidance literature:

2.3.3.3-Tetrafluor-2-methoxy-propionsaeure-methylester, NH3.;

upstream raw materials:

2-fluoro-2-methoxy trifluoropropanoic acid methyl ester