C₂₂H₂₄O

Base Information

• Chemical Name: C₂₂H₂₄O
• CAS No.: 727730-30-5
• Molecular Formula: C₂₂H₂₄O
• Molecular Weight: 304.432
• Mol file: 727730-30-5.mol

Synonyms:C₂₂H₂₄O

Chemical Property of C₂₂H₂₄O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₄O

There total 3 articles about C₂₂H₂₄O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.03%

2-Adamantanone (700-58-3) + 2-Bromobiphenyl (2052-07-5) → C22H24O (727730-30-5)

Guidance literature:

2-Bromobiphenyl; With iodine; magnesium; In diethyl ether; at 35 ℃; for 3h; Inert atmosphere;

2-Adamantanone; In diethyl ether; at 0 - 35 ℃; for 6h;

Reference yield:

2-nitrobiphenyl (86-00-0) → C22H24O (727730-30-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 5% Pd(II)/C(eggshell); hydrogen / ethyl acetate / 24 h / 20 °C / 3800.26 Torr

2.1: hydrogenchloride; sodium nitrite / water / 0.25 h / 0 °C

2.2: 0 - 20 °C

3.1: iodine; magnesium / diethyl ether

With hydrogenchloride; 5% Pd(II)/C(eggshell); hydrogen; iodine; magnesium; sodium nitrite; In diethyl ether; water; ethyl acetate; 3.1: Grignard reaction / 3.2: Grignard reaction;

DOI:10.1021/ma102093t

Reference yield:

2-phenylaniline (90-41-5) → C22H24O (727730-30-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrogenchloride; sodium nitrite / water / 0.25 h / 0 °C

1.2: 0 - 20 °C

2.1: iodine; magnesium / diethyl ether

With hydrogenchloride; iodine; magnesium; sodium nitrite; In diethyl ether; water; 2.1: Grignard reaction / 2.2: Grignard reaction;

DOI:10.1021/ma102093t

upstream raw materials:

2-nitrobiphenyl

2-phenylaniline

2-Adamantanone

2-Bromobiphenyl

Downstream raw materials:

C₂₂H₂₂

2',7'-dibromospiro[adamantane-2,9'-fluorene]

C₃₆H₂₆F₈

2'-bromospiro[adamantane-2,9'-fluorene]