tert-butyl {(1R)-2-[(2S)-2-({2-[3-(acetylamino)prop-1-yn-1-yl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate

Base Information

Chemical Name:tert-butyl {(1R)-2-[(2S)-2-({2-[3-(acetylamino)prop-1-yn-1-yl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate
CAS No.:1246470-19-8
Molecular Formula:C₃₁H₃₅N₅O₅
Molecular Weight:557.649
Hs Code.:

Synonyms:tert-butyl {(1R)-2-[(2S)-2-({2-[3-(acetylamino)prop-1-yn-1-yl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate

Suppliers and Price of tert-butyl {(1R)-2-[(2S)-2-({2-[3-(acetylamino)prop-1-yn-1-yl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyl {(1R)-2-[(2S)-2-({2-[3-(acetylamino)prop-1-yn-1-yl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl {(1R)-2-[(2S)-2-({2-[3-(acetylamino)prop-1-yn-1-yl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate

There total 5 articles about tert-butyl {(1R)-2-[(2S)-2-({2-[3-(acetylamino)prop-1-yn-1-yl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 141972-98-7
(S,R)-1-(2-tert-butoxycarbonylamino-2-phenylacetyl)pyrrolidine-2-carboxylic acid

: C₁₃H₁₃N₃O

: 1246470-19-8
tert-butyl {(1R)-2-[(2S)-2-({2-[3-(acetylamino)prop-1-yn-1-yl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In acetonitrile; at 25 ℃;

Reference yield:

: C₁₆H₁₅N₃O₅

: 1246470-19-8
tert-butyl {(1R)-2-[(2S)-2-({2-[3-(acetylamino)prop-1-yn-1-yl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: iron; ammonium chloride; ethanol / 2 h / 70 °C

2: potassium carbonate; ethanol / 12 h / 25 °C

3: HATU; N-ethyl-N,N-diisopropylamine / acetonitrile / 25 °C

With ethanol; iron; potassium carbonate; ammonium chloride; N-ethyl-N,N-diisopropylamine; HATU; In acetonitrile;

Reference yield:

: C₁₆H₁₇N₃O₃

: 1246470-19-8
tert-butyl {(1R)-2-[(2S)-2-({2-[3-(acetylamino)prop-1-yn-1-yl]-1H-indol-5-yl}carbamoyl)pyrrolidin-1-yl]-2-oxo-1-phenylethyl}carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; ethanol / 12 h / 25 °C

2: HATU; N-ethyl-N,N-diisopropylamine / acetonitrile / 25 °C

With ethanol; potassium carbonate; N-ethyl-N,N-diisopropylamine; HATU; In acetonitrile;