5-Fluoroquinoline-8-sulfonyl chloride

Base Information

Chemical Name:5-Fluoroquinoline-8-sulfonyl chloride
CAS No.:1997-50-8
Molecular Formula:C₉H₅ClFNO₂S
Molecular Weight:245.662
Hs Code.:
European Community (EC) Number:871-733-9
DSSTox Substance ID:DTXSID60590750
Wikidata:Q82484393
Mol file:1997-50-8.mol

Synonyms:1997-50-8;5-Fluoroquinoline-8-sulfonyl chloride;5-Fluoro-8-quinolinesulfonyl chloride;8-Quinolinesulfonyl chloride, 5-fluoro-;8-Quinolinesulfonylchloride, 5-fluoro-;SCHEMBL16049881;DTXSID60590750;YQQUPRGXCYWYBA-UHFFFAOYSA-N;AKOS006222719;DB-296082;EN300-78593

Suppliers and Price of 5-Fluoroquinoline-8-sulfonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
5-Fluoro-8-Quinolinesulfonyl Chloride
10mg
$ 460.00

TRC
5-Fluoro-8-QuinolinesulfonylChloride
10mg
$ 165.00

American Custom Chemicals Corporation
5-FLUORO-8-QUINOLINESULFONYL CHLORIDE 95.00%
5MG
$ 496.58

Total 7 raw suppliers

Chemical Property of 5-Fluoroquinoline-8-sulfonyl chloride

Chemical Property:

Vapor Pressure:3.25E-05mmHg at 25°C
Refractive Index:1.626
Boiling Point:365.6°Cat760mmHg
Flash Point:174.9°C
PSA：55.41000
Density:1.558g/cm³
LogP:3.38220
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:244.9713554
Heavy Atom Count:15
Complexity:330

Purity/Quality:

99% ^*data from raw suppliers

5-Fluoro-8-Quinolinesulfonyl Chloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=C2N=C1)S(=O)(=O)Cl)F
Uses 5-Fluoro-8-Quinolinesulfonyl Chloride may act as a clastogenic compound as well as inhibitor of CYP enzymes due to the quinoline moiety in the substructure. This also leads to antibacterial properties being displayed by the molecule.

Technology Process of 5-Fluoroquinoline-8-sulfonyl chloride

There total 2 articles about 5-Fluoroquinoline-8-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 394-69-4
5-fluoroquinoline

: 1997-50-8
5-fluoroquinoline-8-sulfonyl chloride

Guidance literature:: With chlorosulfonic acid; at 0 - 130 ℃;

Reference yield:

: 611-34-7,146614-41-7
5-Aminoquinoline

: 1997-50-8
5-fluoroquinoline-8-sulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: sodium nitrite; tetrafluoroboric acid / 1 h / 0 °C

2: chlorosulfonic acid / 0 - 130 °C

With chlorosulfonic acid; tetrafluoroboric acid; sodium nitrite;