MTH-DL-PROLINE

Base Information

• Chemical Name: MTH-DL-PROLINE
• CAS No.: 1968-34-9
• Molecular Formula: C₇H₁₀N₂OS
• Molecular Weight: 170.235
• Mol file: 1968-34-9.mol

Synonyms:METHYLTHIOHYDANTOIN-DL-PROLINE;MTH-DL-PROLINE;MTH-DL-Proline Methylthiohydantoin-DL-proline

Chemical Property of MTH-DL-PROLINE

Chemical Property:

• PSA: 55.64000
• LogP: 0.08350
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

MTH-DL-Proline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of MTH-DL-PROLINE

There total 3 articles about MTH-DL-PROLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl thioisocyanate (556-61-6) + L-proline (147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7) → (S)-2-Methyl-3-thioxo-hexahydro-pyrrolo[1,2-c]imidazol-1-one (28868-23-7,1968-34-9)

Guidance literature:

With sodium carbonate; In 1,4-dioxane; water; 1. room temperature, 3 h; 2. reflux, 1 h;

Reference yield:

methyl thioisocyanate (556-61-6) + rac-Pro-OH (609-36-9,25191-13-3,37159-97-0,4305-67-3,4607-28-7) → Methylthiohydantoin-Derivat v. Prolin (22712-58-9,145552-40-5,1968-34-9)

Guidance literature:

With 1,4-dioxane; anschliessendes Erhitzen mit wss.HCl;

DOI:10.1039/jr9580003489

Reference yield:

→ Methylthiohydantoin-Derivat v. Prolin (22712-58-9,145552-40-5,1968-34-9)

Guidance literature:

DL-Prolin-hydrochlorid, 1) Methylisothiocyanat (H2O/40 grad/pH 9), 2) Δ, wss. HCl;

upstream raw materials:

methyl thioisocyanate

rac-Pro-OH

L-proline