N-(6-(diethylamino)-9-(2-((2-(4-((2,5-dioxo-3-phenoxypyrrol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)carbonyl)phenyl)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride

Base Information

• Chemical Name: N-(6-(diethylamino)-9-(2-((2-(4-((2,5-dioxo-3-phenoxypyrrol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)carbonyl)phenyl)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride
• CAS No.: 1616886-78-2
• Molecular Formula: C₄₃H₄₃N₆O₆*Cl
• Molecular Weight: 775.304
• Mol file: 1616886-78-2.mol

Synonyms:N-(6-(diethylamino)-9-(2-((2-(4-((2,5-dioxo-3-phenoxypyrrol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)carbonyl)phenyl)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride

Chemical Property of N-(6-(diethylamino)-9-(2-((2-(4-((2,5-dioxo-3-phenoxypyrrol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)carbonyl)phenyl)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(6-(diethylamino)-9-(2-((2-(4-((2,5-dioxo-3-phenoxypyrrol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)carbonyl)phenyl)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride

There total 3 articles about N-(6-(diethylamino)-9-(2-((2-(4-((2,5-dioxo-3-phenoxypyrrol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)carbonyl)phenyl)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

N-(9-(2-((2-azidoethoxy)carbonyl)phenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethylethaniminium chloride (1033001-11-4) + 3-phenoxy-1-(prop-2-ynyl)pyrrole-2,5-dione → N-(6-(diethylamino)-9-(2-((2-(4-((2,5-dioxo-3-phenoxypyrrol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)carbonyl)phenyl)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride (1616886-78-2)

Guidance literature:

With copper(l) iodide; acetic acid; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1039/c4cc02107j

Reference yield:

methyl (3-phenoxypyrrole-2,5-dione)-1-carboxylate (1616886-86-2) → N-(6-(diethylamino)-9-(2-((2-(4-((2,5-dioxo-3-phenoxypyrrol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)carbonyl)phenyl)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride (1616886-78-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 1.5 h / 20 °C / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine; copper(l) iodide; acetic acid / dichloromethane / 4 h / 20 °C / Inert atmosphere

With copper(l) iodide; acetic acid; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1039/c4cc02107j

Reference yield:

3-phenoxypyrrole-2,5-dione (1616886-85-1) → N-(6-(diethylamino)-9-(2-((2-(4-((2,5-dioxo-3-phenoxypyrrol-1-yl)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)carbonyl)phenyl)-3H-xanthen-3-ylidene)-N-ethylethanaminium chloride (1616886-78-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 4-methyl-morpholine / dichloromethane / 0.5 h / 20 °C / Inert atmosphere

2: dichloromethane / 1.5 h / 20 °C / Inert atmosphere

3: N-ethyl-N,N-diisopropylamine; copper(l) iodide; acetic acid / dichloromethane / 4 h / 20 °C / Inert atmosphere

With 4-methyl-morpholine; copper(l) iodide; acetic acid; N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1039/c4cc02107j

upstream raw materials:

3-phenoxypyrrole-2,5-dione

methyl (3-phenoxypyrrole-2,5-dione)-1-carboxylate

N-(9-(2-((2-azidoethoxy)carbonyl)phenyl)-6-(diethylamino)-3H-xanthen-3-ylidene)-N-ethylethaniminium chloride