4-Acetamidophenyl trifluoromethyl sulphoxide

Base Information

Chemical Name:4-Acetamidophenyl trifluoromethyl sulphoxide
CAS No.:1948-04-5
Molecular Formula:C9H8 F3 N O2 S
Molecular Weight:251.229
Hs Code.:
DSSTox Substance ID:DTXSID10460232
Mol file:1948-04-5.mol

Synonyms:1948-04-5;4-Acetamidophenyl trifluoromethyl sulphoxide;DTXSID10460232;N-[4-(Trifluoromethanesulfinyl)phenyl]acetamide

Suppliers and Price of 4-Acetamidophenyl trifluoromethyl sulphoxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-Acetamidophenyl trifluoromethyl sulphoxide

Chemical Property:

PSA：65.38000
LogP:3.21110
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:251.02278416
Heavy Atom Count:16
Complexity:285

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)S(=O)C(F)(F)F

Technology Process of 4-Acetamidophenyl trifluoromethyl sulphoxide

There total 2 articles about 4-Acetamidophenyl trifluoromethyl sulphoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 351-81-5
4-trifluoromethylthioacetanilide

: 1948-04-5
N-(4-((trifluoromethyl)sulfinyl)phenyl)acetamide

Guidance literature:: With dihydrogen peroxide; trifluoroacetic acid; In water; at 25 - 28 ℃; for 24h;
DOI:10.3390/molecules24071249

Reference yield: 57.0%

: 2926-29-6
Langlois reagent

: 103-84-4
Acetanilid

: 708-67-8
4-aminophenyl trifluoromethylsulfoxide

: 1948-04-5
N-(4-((trifluoromethyl)sulfinyl)phenyl)acetamide

Guidance literature:: With trifluoromethylsulfonic anhydride; at 20 ℃;
DOI:10.1055/s-2001-12316

Reference yield:

: 1948-04-5
N-(4-((trifluoromethyl)sulfinyl)phenyl)acetamide

: 1948-07-8
(3,4-Diamino-phenyl)-trifluormethyl-sulfoxid

Guidance literature:: Multi-step reaction with 2 steps

1: (i) HNO₃, H₂SO₄, (ii) aq. HCl

2: SnCl₂, aq. HCl / methanol

With hydrogenchloride; tin(ll) chloride; In methanol;