(E)-ethyl 3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-enoate

Base Information

Chemical Name:(E)-ethyl 3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-enoate
CAS No.:1085372-83-3
Molecular Formula:C₃₀H₃₁NO₃
Molecular Weight:453.581
Hs Code.:

Synonyms:(E)-ethyl 3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-enoate

Suppliers and Price of (E)-ethyl 3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-enoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-ethyl 3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-enoate

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Technology Process of (E)-ethyl 3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-enoate

There total 1 articles about (E)-ethyl 3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 10544-63-5
ethyl crotonate

: 1085372-81-1
C₂₄H₂₂BrNO

: 1085372-83-3
(E)-ethyl 3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-enoate

Guidance literature:: With triethylamine; tris-(o-tolyl)phosphine; palladium dichloride; In acetonitrile; for 16h; Inert atmosphere; Reflux;
DOI:10.1021/ol8023105

Reference yield: 80.0%

: 1085372-83-3
(E)-ethyl 3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-enoate

: 1443437-20-4
(E)-3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-en-1-ol

Guidance literature:: With diisobutylaluminium hydride; In toluene; at -55 - 5 ℃; Inert atmosphere;
DOI:10.1002/chem.201202413

Reference yield:

: 1085372-83-3
(E)-ethyl 3-(1-benzyl-4-(1-(benzyloxy)ethyl)-1H-indol-7-yl)but-2-enoate

: 1085372-36-6
(E)-ethyl 3-(1-benzyl-4-ethyl-1H-indol-7-yl)but-2-enoate

Guidance literature:: With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; water; for 8h; under 7600.51 Torr;
DOI:10.1021/ol8023105