benzyl-[5-bromo-6'-(1-methyl-1H-pyrazol-3-yl)-[3,4']bipyridinyl-2'-yl]-amine

Base Information

Chemical Name:benzyl-[5-bromo-6'-(1-methyl-1H-pyrazol-3-yl)-[3,4']bipyridinyl-2'-yl]-amine
CAS No.:1171043-87-0
Molecular Formula:C₂₁H₁₈BrN₅
Molecular Weight:420.311
Hs Code.:

Synonyms:benzyl-[5-bromo-6'-(1-methyl-1H-pyrazol-3-yl)-[3,4']bipyridinyl-2'-yl]-amine

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Chemical Property of benzyl-[5-bromo-6'-(1-methyl-1H-pyrazol-3-yl)-[3,4']bipyridinyl-2'-yl]-amine

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Technology Process of benzyl-[5-bromo-6'-(1-methyl-1H-pyrazol-3-yl)-[3,4']bipyridinyl-2'-yl]-amine

There total 3 articles about benzyl-[5-bromo-6'-(1-methyl-1H-pyrazol-3-yl)-[3,4']bipyridinyl-2'-yl]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (E)-3-(5-bromo-pyridin-3-yl)-1-(1-methyl-1H-pyrazol-3-yl)-propenone

: 111198-08-4
1-(cyanomethyl)benzotriazole

: 100-46-9
benzylamine

: 1171043-87-0
benzyl-[5-bromo-6'-(1-methyl-1H-pyrazol-3-yl)-[3,4']bipyridinyl-2'-yl]-amine

Guidance literature:: In ethanol; at 120 ℃; Microwave radiation;

Reference yield:

: 113118-81-3
5-bromopyridine-3-carbaldehyde

: 1171043-87-0
benzyl-[5-bromo-6'-(1-methyl-1H-pyrazol-3-yl)-[3,4']bipyridinyl-2'-yl]-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 20 °C / Inert atmosphere of argon

2: ethanol / 120 °C / Microwave radiation

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; ethanol;

Reference yield:

: 137890-04-1
1-(1-methyl-1H-pyrazol-3-yl)acetaldehyde

: 1171043-87-0
benzyl-[5-bromo-6'-(1-methyl-1H-pyrazol-3-yl)-[3,4']bipyridinyl-2'-yl]-amine

Guidance literature:: Multi-step reaction with 2 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 20 °C / Inert atmosphere of argon

2: ethanol / 120 °C / Microwave radiation

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; ethanol;