6-Methyl-2-(trifluoromethyl)quinoline

Base Information

Chemical Name:6-Methyl-2-(trifluoromethyl)quinoline
CAS No.:1860-47-5
Molecular Formula:C₁₁H₈F₃N
Molecular Weight:211.186
Hs Code.:2933499090
DSSTox Substance ID:DTXSID50379657
Nikkaji Number:J2.244.583I
Wikidata:Q82169559
Mol file:1860-47-5.mol

Synonyms:6-methyl-2-(trifluoromethyl)quinoline;1860-47-5;SCHEMBL13347730;DTXSID50379657;AXLVKRXDCFWRLD-UHFFFAOYSA-N;6-Methyl-2-trifluoromethylquinoline;MFCD00219659;2-(Trifluoromethyl)-6-methylquinoline;AKOS000320170;6-methyl-2-(trifluoromethyl)-quinoline;FT-0621209;A813002

Suppliers and Price of 6-Methyl-2-(trifluoromethyl)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
6-METHYL-2-(TRIFLUOROMETHYL)QUINOLINE 95
5g
$ 1467.00

American Custom Chemicals Corporation
6-METHYL-2-(TRIFLUOROMETHYL)QUINOLINE 95.00%
5MG
$ 498.74

Total 12 raw suppliers

Chemical Property of 6-Methyl-2-(trifluoromethyl)quinoline

Chemical Property:

Vapor Pressure:0.0873mmHg at 25°C
Refractive Index:1.533
Boiling Point:248.7°Cat760mmHg
Flash Point:104.2°C
PSA：12.89000
Density:1.267g/cm³
LogP:3.56200
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:211.06088375
Heavy Atom Count:15
Complexity:226

Purity/Quality:

97% ^*data from raw suppliers

6-METHYL-2-(TRIFLUOROMETHYL)QUINOLINE 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)N=C(C=C2)C(F)(F)F

Technology Process of 6-Methyl-2-(trifluoromethyl)quinoline

There total 19 articles about 6-Methyl-2-(trifluoromethyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1195931-68-0
6-methyl-2-(trifluoromethyl)-quinolin-4-yl trifluoromethanesulfonate

: 1860-47-5
6-methyl-2-(trifluoromethyl)quinoline

Guidance literature:: With triethylsilane; 1,3-bis-(diphenylphosphino)propane; palladium diacetate; In N,N-dimethyl-formamide; at 90 ℃; for 2h; Inert atmosphere; Sealed tube;
DOI:10.1021/jacs.5b09308

Reference yield: 91.0%

: 1-iodo-3,3,4,4,4-pentafluorobutyl acetate

: 106-49-0,12221-03-3
p-toluidine

: 1860-47-5
6-methyl-2-(trifluoromethyl)quinoline

Guidance literature:: In dichloromethane; for 12h; Heating;
DOI:10.1021/jo050586d

Reference yield: 79.0%

: 2-iodo-6-methylquinoline

: 2923-16-2
potassium trifluoroacetate

: 1860-47-5
6-methyl-2-(trifluoromethyl)quinoline

Guidance literature:: With pyridine; copper(l) iodide; In 1-methyl-pyrrolidin-2-one; ethyl acetate; at 200 - 210 ℃; Inert atmosphere;
DOI:10.1002/anie.201306094