3,3,3-TRIFLUORO-2,2-BIS(TRIFLUOROMETHYL)PROPANOYL FLUORIDE

Base Information

• Chemical Name: 3,3,3-TRIFLUORO-2,2-BIS(TRIFLUOROMETHYL)PROPANOYL FLUORIDE
• CAS No.: 1813-18-9
• Molecular Formula: C5F10 O
• Molecular Weight: 266.038
• Hs Code.: 2915900090
• Mol file: 1813-18-9.mol

Synonyms:Propionylfluoride, 3,3,3-trifluoro-2,2-bis(trifluoromethyl)- (7CI); Propionyl fluoride,trifluoro-2,2-bis(trifluoromethyl)- (8CI); Perfluoropivaloyl fluoride;Perfluoropivalyl fluoride

Chemical Property of 3,3,3-TRIFLUORO-2,2-BIS(TRIFLUOROMETHYL)PROPANOYL FLUORIDE

Chemical Property:

• Boiling Point: 27-30°C
• PSA: 17.07000
• LogP: 3.15580

Purity/Quality:

99%, ^*data from raw suppliers

3,3,3-TRIFLUORO-2,2-BIS(TRIFLUOROMETHYL)PROPANOYL FLUORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Statements: 34
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,3,3-TRIFLUORO-2,2-BIS(TRIFLUOROMETHYL)PROPANOYL FLUORIDE

There total 9 articles about 3,3,3-TRIFLUORO-2,2-BIS(TRIFLUOROMETHYL)PROPANOYL FLUORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

perfluoroisobutylene (382-21-8) + 4-dimethylamino-benzaldehyde (100-10-7) → 3,3,3-trifluoro-2,2-bis-trifluoromethyl-propionyl fluoride (1813-18-9) + 1,1-bis(trifluoromethyl)-2-<-p-(dimethylamino)phenyl>ethylene

Guidance literature:

In acetonitrile; at 20 ℃; for 360h;

DOI:10.1007/BF00950302

Reference yield: 74.0%

neopentyl chloride (753-89-9) → perfluoroisobutylene (354-92-7) + 3,3,3-trifluoro-2,2-bis-trifluoromethyl-propionyl fluoride (1813-18-9) + 1-Chloro-F-2-methylpropane (10537-60-7) + perfluoroneopentyl chloride (87136-72-9)

Guidance literature:

With fluorine; for 3h; Yield given; Irradiation; aerosol;

DOI:10.1021/jo00173a035

Reference yield: 70.0%

2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-Tricosafluoro-dodecanoic acid 1,1,3,3,3-pentafluoro-2,2-bis-trifluoromethyl-propyl ester → tricosafluoro-dodecanoyl fluoride + 3,3,3-trifluoro-2,2-bis-trifluoromethyl-propionyl fluoride (1813-18-9)

Guidance literature:

at 243 ℃;

DOI:10.1021/ja980727b

upstream raw materials:

pivaloyl fluoride

phosgene

perfluoroisobutylene

Carbonyl fluoride

Downstream raw materials:

phenylperfluoroisobutylene

phenyl perfluoro-tert-butyl ketone

Refernces

• 1、 Adcock,Lagow. "". . p. 7588. Retrieved 1974.
• 2、 Huang, Hsu-Nan,Lagow, Richard J.. "Synthesis of Functional Perfluorinated Resins, Branched Perfluorinated Ethers and Perfluoroalkanoyl Fluorides". . p. 871 - 875. Retrieved 2007/10/02.
• 3、 Gontar, A. F.,Bykhovskaya, E. G.,Vinogradov, A. S.,Knunyants, I. L.. "REACTIONS OF BIS(TRIFLUOROMETHYL)CARBAMOYL FLUORIDE WITH NUCLEOPHILIC REAGENTS". . p. 2188 - 2191. Retrieved 2007/10/02.