2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethyl-4-methylphenylsulphonate

Base Information

• Chemical Name: 2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethyl-4-methylphenylsulphonate
• CAS No.: 530093-83-5
• Molecular Formula: C₂₀H₂₂O₃S
• Molecular Weight: 342.459
• Mol file: 530093-83-5.mol

Synonyms:2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethyl-4-methylphenylsulphonate

Chemical Property of 2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethyl-4-methylphenylsulphonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethyl-4-methylphenylsulphonate

There total 3 articles about 2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethyl-4-methylphenylsulphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

p-toluenesulfonyl chloride (98-59-9) + 2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethanol (530093-94-8) → 2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethyl-4-methylphenylsulphonate (530093-83-5)

Guidance literature:

With pyridine; In chloroform; at 20 ℃; for 3h;

DOI:10.1016/S0040-4039(03)00093-5

Reference yield:

7-methyl-3,4-dihydro-2H-naphthalen-1-one (22009-37-6) → 2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethyl-4-methylphenylsulphonate (530093-83-5)

Guidance literature:

Multi-step reaction with 3 steps

1: NaBH₄; PEG-400 / 65 °C

2: 84 percent / pyridine / CHCl₃ / 3 h / 20 °C

With pyridine; PEG-400; sodium tetrahydroborate; In chloroform; 1: Reformatsky reaction;

DOI:10.1016/S0040-4039(03)00093-5

Reference yield:

ethyl (7-methyl-3,4-dihydronaphthalen-1-yl)acetate (108299-64-5) → 2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethyl-4-methylphenylsulphonate (530093-83-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄; PEG-400 / 65 °C

2: 84 percent / pyridine / CHCl₃ / 3 h / 20 °C

With pyridine; PEG-400; sodium tetrahydroborate; In chloroform;

DOI:10.1016/S0040-4039(03)00093-5

upstream raw materials:

p-toluenesulfonyl chloride

2-(3,4-dihydro-7-methyl-1-naphthalenyl)ethanol

7-methyl-3,4-dihydro-2H-naphthalen-1-one

ethyl (7-methyl-3,4-dihydronaphthalen-1-yl)acetate

Downstream raw materials:

16,17-dihydro-7-methyl-15H-cyclopenta[a]phenanthrene