2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-oxo-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester

Base Information

Chemical Name:2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-oxo-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester
CAS No.:158743-63-6
Molecular Formula:C₂₇H₂₆N₄O₅S₃
Molecular Weight:582.725
Hs Code.:

Synonyms:2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-oxo-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester

Suppliers and Price of 2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-oxo-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-oxo-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-oxo-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester

There total 2 articles about 2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-oxo-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 75849-83-1
sodium 1,2,3-thiadiazole-5-thiolate

: 158743-65-8
2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-4-chloro-3-oxo-butyric acid benzhydryl ester

: 158743-63-6
2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-oxo-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester

Guidance literature:: In ethanol; at 0 ℃; for 2h;
DOI:10.7164/antibiotics.47.453

Reference yield:

: diphenylmethyl 2-(2-tert-butoxycarbonylaminothiazol-4-yl)acetate

: 158743-63-6
2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-oxo-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 1M lithium hexamethyldisilazane / 1.) THF, -78 deg C, 30 min, 2.) THF, 1 h

2: 65 percent / ethanol / 2 h / 0 °C

With lithium hexamethyldisilazane; In ethanol;
DOI:10.7164/antibiotics.47.453

Reference yield:

: 158743-63-6
2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-oxo-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester

: 158743-67-0
2-(2-tert-Butoxycarbonylamino-thiazol-4-yl)-3-hydroxy-4-([1,2,3]thiadiazol-5-ylsulfanyl)-butyric acid benzhydryl ester

Guidance literature:: With sodium tetrahydroborate; In methanol; dichloromethane; at -20 ℃; for 0.333333h; Yield given;
DOI:10.7164/antibiotics.47.453