1H-Indole-7-carboxamide

Base Information

• Chemical Name: 1H-Indole-7-carboxamide
• CAS No.: 1670-89-9
• Molecular Formula: C9H8 N2 O
• Molecular Weight: 160.17
• Hs Code.: 2933990090
• ChEMBL ID: CHEMBL1688213
• DSSTox Substance ID: DTXSID10540109
• Wikidata: Q82415993
• Mol file: 1670-89-9.mol

Synonyms:1H-INDOLE-7-CARBOXAMIDE;1670-89-9;1H-Indole-7-carboxylic acid amide;1H-Indole-7-carboxamide(9CI);CHEMBL1688213;MFCD00572866;SCHEMBL1651352;DTXSID10540109;OXCXIABGNNQZOF-UHFFFAOYSA-N;BAA67089;BDBM50339017;AKOS014316237;SB34151;SY211938;TS-02126;CS-0216088;EN300-332821;F18358;A846453;Z1255438908

Chemical Property of 1H-Indole-7-carboxamide

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.717
• Boiling Point: 457.624°C at 760 mmHg
• Flash Point: 230.563°C
• PSA: 58.88000
• Density: 1.328g/cm³
• LogP: 1.96710
• Storage Temp.: 2-8°C
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 160.063662883
• Heavy Atom Count: 12
• Complexity: 193

Purity/Quality:

97% ^*data from raw suppliers

1H-Indole-7-carboxamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=C1)C(=O)N)NC=C2

Technology Process of 1H-Indole-7-carboxamide

There total 1 articles about 1H-Indole-7-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

trans-3-cyano-β-dimethylamino-2-nitrostyrene (114343-99-6) → 1H-indole-7-carbonitrile (96631-87-7) + 7-carboxamidoindole (1670-89-9) + β-(2-amino-3-cyanophenyl)ethylamine (96631-88-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In benzene; for 2h; under 2585.7 Torr;

upstream raw materials:

trans-3-cyano-β-dimethylamino-2-nitrostyrene