2-Chloro-6-fluoro-N-hydroxybenzimidamide

Base Information

Chemical Name:2-Chloro-6-fluoro-N-hydroxybenzimidamide
CAS No.:1643-74-9
Molecular Formula:C₇H₆ClFN₂O
Molecular Weight:188.589
Hs Code.:
Mol file:1643-74-9.mol

Synonyms:1643-74-9;2-Chloro-6-fluoro-N-hydroxybenzimidamide;2-CHLORO-6-FLUORO-N-HYDROXY-BENZAMIDINE;Benzenecarboximidamide, 2-chloro-6-fluoro-N-hydroxy-;AKOS000134046;AKOS006242960;AS-69076;EN300-1599687;2-chloro-6-fluoro-N-hydroxybenzene-1-carboximidamide;(Z)-2-chloro-6-fluoro-N'-hydroxybenzene-1-carboximidamide

Suppliers and Price of 2-Chloro-6-fluoro-N-hydroxybenzimidamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-CHLORO-6-FLUORO-N-HYDROXY-BENZAMIDINE 95.00%
5MG
$ 495.95

Total 9 raw suppliers

Chemical Property of 2-Chloro-6-fluoro-N-hydroxybenzimidamide

Chemical Property:

Melting Point:131-134 °C
Boiling Point:279.4±50.0 °C(Predicted)
PKA:13.65±0.50(Predicted)
PSA：56.11000
Density:1.47±0.1 g/cm3(Predicted)
LogP:2.27390
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:188.0152687
Heavy Atom Count:12
Complexity:188

Purity/Quality:

97% ^*data from raw suppliers

2-CHLORO-6-FLUORO-N-HYDROXY-BENZAMIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)Cl)C(=NO)N)F
Isomeric SMILES:C1=CC(=C(C(=C1)Cl)/C(=N/O)/N)F

Technology Process of 2-Chloro-6-fluoro-N-hydroxybenzimidamide

There total 2 articles about 2-Chloro-6-fluoro-N-hydroxybenzimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1643-74-9
2-chloro-6-fluorobenzamide oxime

Guidance literature:

Reference yield:

: 1643-74-9
2-Chloro-6-fluoro-N-hydroxy-benzamidine

Guidance literature:: entspr. α-Trichlorbenzaldoxim;

Reference yield:

: 1643-74-9
2-Chloro-6-fluoro-N-hydroxy-benzamidine

: 110722-38-8
{3-[3-(2-Chloro-6-fluoro-phenyl)-[1,2,4]oxadiazol-5-ylmethyl]-4-oxo-3,4-dihydro-phthalazin-1-yl}-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

2: toluene / Heating

3: 1.) NaH / 1.) DMF, RT, 30 min, 2.) DMF, RT, 30 min

With sodium hydride; In toluene;
DOI:10.1021/jm00081a006