C₄₇H₅₅N₅O₇S₄

Base Information

• Chemical Name: C₄₇H₅₅N₅O₇S₄
• CAS No.: 1256478-21-3
• Molecular Formula: C₄₇H₅₅N₅O₇S₄
• Molecular Weight: 930.247
• Mol file: 1256478-21-3.mol

Synonyms:C₄₇H₅₅N₅O₇S₄

Chemical Property of C₄₇H₅₅N₅O₇S₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₇H₅₅N₅O₇S₄

There total 15 articles about C₄₇H₅₅N₅O₇S₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

C21H25N3O5S2 (1219077-49-2) + (E)-26-ethynyl-2-oxa-10,11-dithia-21,22-diaza-tricyclo[22.3.1.14,8]nonacosa-1(27),4(29),5,7,22,24(28),25-heptaen-20-one (1256478-17-7) → C47H55N5O7S4 (1256478-21-3)

Guidance literature:

With tetrakis(actonitrile)copper(I) hexafluorophosphate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In tetrahydrofuran; methanol; dichloromethane; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1021/ja106486b

Reference yield:

methyl 9-iodononanoate (75452-47-0) → C47H55N5O7S4 (1256478-21-3)

Guidance literature:

Multi-step reaction with 6 steps

1.1: N,N-dimethyl-formamide / 1 h / 20 °C

2.1: methanol; sodium methylate / 3 h / 20 °C

3.1: hydrazine hydrate / ethanol / 16 h / Reflux

4.1: acetic acid / methanol / 2 h / 20 °C / Inert atmosphere

5.1: sodium methylate / methanol; dichloromethane / 2 h / 20 °C / Inert atmosphere

5.2: 20 °C / Inert atmosphere

6.1: tetrakis(actonitrile)copper(I) hexafluorophosphate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / tetrahydrofuran; methanol; dichloromethane / 16 h / 20 °C / Inert atmosphere

With methanol; tetrakis(actonitrile)copper(I) hexafluorophosphate; sodium methylate; hydrazine hydrate; acetic acid; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja106486b

Reference yield:

azelaic monomethyl ester (2104-19-0) → C47H55N5O7S4 (1256478-21-3)

Guidance literature:

Multi-step reaction with 10 steps

1.1: triethylamine / tetrahydrofuran / 1 h / -5 °C

2.1: sodium tetrahydroborate / water / 1 h / 0 °C

3.1: triethylamine / dichloromethane / 1 h / 0 °C

4.1: sodium iodide / acetone / 12 h / 20 °C

5.1: N,N-dimethyl-formamide / 1 h / 20 °C

6.1: methanol; sodium methylate / 3 h / 20 °C

7.1: hydrazine hydrate / ethanol / 16 h / Reflux

8.1: acetic acid / methanol / 2 h / 20 °C / Inert atmosphere

9.1: sodium methylate / methanol; dichloromethane / 2 h / 20 °C / Inert atmosphere

9.2: 20 °C / Inert atmosphere

10.1: tetrakis(actonitrile)copper(I) hexafluorophosphate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine / tetrahydrofuran; methanol; dichloromethane / 16 h / 20 °C / Inert atmosphere

With methanol; sodium tetrahydroborate; tetrakis(actonitrile)copper(I) hexafluorophosphate; sodium methylate; hydrazine hydrate; acetic acid; triethylamine; sodium iodide; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetone;

DOI:10.1021/ja106486b

upstream raw materials:

3-ethynyl-5-hydroxybenzaldehyde

9-mercaptononanehydrazide

C₁₉H₁₆O₃S

(E)-S-3-((3-ethynyl-5-((2-(9-mercaptononanoyl)hydrazono)methyl)phenoxy)methyl)benzylethanethioate

Downstream raw materials:

C₄₅H₄₉N₅O₆S₄