HOP-21(22)-ENE

Base Information

• Chemical Name: HOP-21(22)-ENE
• CAS No.: 1615-92-5
• Molecular Formula: C30H50
• Molecular Weight: 410.727
• Mol file: 1615-92-5.mol

Synonyms:Hopene a(6CI); 17bH-Hop-21(22)-ene; Hop-21-ene

Chemical Property of HOP-21(22)-ENE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.51
• Boiling Point: 460.703°C at 760 mmHg
• Flash Point: 232.134°C
• PSA: 0.00000
• Density: 0.942g/cm³
• LogP: 9.19810
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s): F,Xn,N
• Hazard Codes: F,Xn,N
• Statements: 11-38-50/53-65-67
• Safety Statements: 60-61-62

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of HOP-21(22)-ENE

There total 5 articles about HOP-21(22)-ENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hopan-22-ol (1721-59-1) → hop-22(29)-ene (1615-92-5) + diploptene (1615-91-4,1812-64-2,33323-60-3,33323-61-4,43206-60-6)

Guidance literature:

With acetic anhydride; potassium carbonate; for 1h; Yield given. Yields of byproduct given; Heating;

Reference yield:

2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene (111-02-4) → hop-22(29)-ene (1615-92-5) + diploptene (1615-91-4,1812-64-2,33323-60-3,33323-61-4,43206-60-6) + hopan-22-ol (1721-59-1)

Guidance literature:

With sodium citrate buffer; Alicyclobacillus acidocaldarus squlaene-hopene cyclase Q₂₆₂G; Triton X-100; at 45 ℃; for 1h; pH=6.0; Further Variations:; Temperatures; Reagents; Enzyme kinetics; Product distribution;

DOI:10.1271/bbb.68.728

Reference yield:

2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene (111-02-4) → neohop-13(18)-ene (21681-17-4) + hop-22(29)-ene (1615-92-5) + diploptene (1615-91-4,1812-64-2,33323-60-3,33323-61-4,43206-60-6) + hopan-22-ol (1721-59-1)

Guidance literature:

With 5'-GGATGTTTCAGGGGTCGATATCGCCGGTGTG-3'; In aq. buffer; at 45 ℃; for 12h; Enzymatic reaction;

DOI:10.1002/cbic.201800281

upstream raw materials:

hopan-22-ol

2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene

hydroxyisohopane

Downstream raw materials:

17αH-trisnorhopanone

trisnorhopanone

22,29,30-trinor(17αH)-hopan-21-one

trisnor(17α)hopan-21-one

Refernces

• 1、 Sato, Tsutomu,Kouda, Masanori,Hoshino, Tsutomu. "Site-directed mutagenesis experiments on the putative deprotonation site of squalene-hopene cyclase from Alicyclobacillus acidocaldarius". . p. 728 - 738. Retrieved 2007/10/03.
• 2、 Ageta, Hiroyuki,Shiojima, Kenji,Arai, Yoko. "Acid-Induced Rearrangement of Triterpenoid Hydrocarbons Belonging to the Hopane and Migrated Hopane Series". . p. 2705 - 2716. Retrieved 2007/10/02.