4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)-4-(2-vinylphenyl)but-1-en-2-yl)-1,3,2-dioxaborolane

Base Information

• Chemical Name: 4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)-4-(2-vinylphenyl)but-1-en-2-yl)-1,3,2-dioxaborolane
• CAS No.: 1509927-12-1
• Molecular Formula: C₂₄H₂₉BO₄S
• Molecular Weight: 424.369
• Mol file: 1509927-12-1.mol

Synonyms:4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)-4-(2-vinylphenyl)but-1-en-2-yl)-1,3,2-dioxaborolane

Chemical Property of 4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)-4-(2-vinylphenyl)but-1-en-2-yl)-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)-4-(2-vinylphenyl)but-1-en-2-yl)-1,3,2-dioxaborolane

There total 1 articles about 4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)-4-(2-vinylphenyl)but-1-en-2-yl)-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

n-butyllithium (109-72-8,29786-93-4) + 4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)prop-1-en-2-yl)-1,3,2-dioxaborolane (1424999-26-7) + diisopropylamine (108-18-9) + 1-iodomethyl-2-vinyl-benzene (171550-83-7) → 4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)-4-(2-vinylphenyl)but-1-en-2-yl)-1,3,2-dioxaborolane (1509927-12-1)

Guidance literature:

n-butyllithium; 4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)prop-1-en-2-yl)-1,3,2-dioxaborolane; diisopropylamine; In tetrahydrofuran; at -78 ℃; for 2h;

1-iodomethyl-2-vinyl-benzene; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1021/ol4029918

Reference yield: 95.0%

4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)-4-(2-vinylphenyl)but-1-en-2-yl)-1,3,2-dioxaborolane (1509927-12-1) → 4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)-3,4-dihydronaphthalen-2-yl)-1,3,2-dioxaborolane (1509927-23-4)

Guidance literature:

With Hoveyda-Grubbs catalyst second generation; p-benzoquinone; In toluene; at 110 ℃; for 24h; Inert atmosphere; Sealed tube;

DOI:10.1021/ol4029918

upstream raw materials:

n-butyllithium

4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)prop-1-en-2-yl)-1,3,2-dioxaborolane

diisopropylamine

1-iodomethyl-2-vinyl-benzene

Downstream raw materials:

4,4,5,5-tetramethyl-2-(3-(phenylsulfonyl)-3,4-dihydronaphthalen-2-yl)-1,3,2-dioxaborolane